{"id":"W2118374554","doi":"10.1093/jac/dkn422","title":"Co-encapsulation of gallium with gentamicin in liposomes enhances antimicrobial activity of gentamicin against Pseudomonas aeruginosa","year":2008,"lang":"en","type":"article","venue":"Journal of Antimicrobial Chemotherapy","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":140,"is_retracted":false,"has_abstract":true,"ca_institutions":"NOSM University; Lakehead University; Laurentian University","funders":"","keywords":"Gentamicin; Pseudomonas aeruginosa; Microbiology; Minimum inhibitory concentration; Antimicrobial; Biofilm; Aminoglycoside; Chemistry; Quorum sensing; Viability assay; Sputum; Minimum bactericidal concentration; Antibiotics; Biology; Pharmacology; Bacteria; In vitro; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002210627,0.0002277978,0.0005433739,0.0001713675,0.00004972449,0.00001094121,0.0001857708,0.0001868661,0.0000119871],"category_scores_gemma":[0.00001122479,0.0001928305,0.0001956285,0.0001537484,0.0002429237,0.00003000105,0.00001893207,0.0001668242,6.645539e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002936783,"about_ca_system_score_gemma":0.0002051116,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005983731,"about_ca_topic_score_gemma":0.00003406128,"domain_scores_codex":[0.9986261,0.00008536923,0.0006484626,0.000218091,0.000178047,0.0002439055],"domain_scores_gemma":[0.9986003,0.00001492326,0.0009257305,0.0001902728,0.0002153497,0.00005343169],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00203583,0.000358307,0.01000504,0.00004963119,0.0001196891,0.00001628939,0.0002447863,0.0001802448,0.9853536,7.326541e-7,0.0007977396,0.0008380561],"study_design_scores_gemma":[0.002580638,0.0005639659,0.0178053,0.0001565838,0.0000184922,0.0002170476,0.00002565887,0.00001057616,0.9779814,5.4124e-7,0.000443101,0.000196697],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990207,0.00007918994,0.0002083883,0.0002482087,0.0001867525,0.0001620445,0.00002562031,0.000003138999,0.00006593535],"genre_scores_gemma":[0.9948229,0.002104041,0.002427141,0.0003092694,0.000257815,2.057997e-7,0.00002407297,0.0000290371,0.00002553569],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007800263,"threshold_uncertainty_score":0.7863401,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008610498917418805,"score_gpt":0.2333320319672101,"score_spread":0.2247215330497913,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}