{"id":"W2118442022","doi":"10.1074/jbc.m102858200","title":"Noncovalent Interaction between Ubiquitin and the Human DNA Repair Protein Mms2 Is Required for Ubc13-mediated Polyubiquitination","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":154,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; University of Alberta","funders":"","keywords":"Ubiquitin; DNA; Chemistry; Ubiquitins; Ubiquitin-conjugating enzyme; Cell biology; Biochemistry; Biology; Ubiquitin ligase; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001014873,0.0001857085,0.000301153,0.00002425714,0.0001594571,0.00003777259,0.0002179375,0.000314056,0.00006572964],"category_scores_gemma":[0.0006428884,0.0001175529,0.0002819494,0.00007072526,0.0002311961,0.00001120323,0.00009451295,0.0002389937,0.000001616452],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003449785,"about_ca_system_score_gemma":0.00004752701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003263352,"about_ca_topic_score_gemma":6.191314e-7,"domain_scores_codex":[0.9986546,0.0001163007,0.0005748331,0.0002586828,0.0001569176,0.0002386822],"domain_scores_gemma":[0.9988057,0.0001039104,0.0005507669,0.0001845593,0.00023965,0.0001153995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000694534,0.00005869983,0.001715885,0.00004961028,0.00008729343,0.000005391138,0.00004783721,4.411149e-7,0.9952589,0.00003118036,0.0006322015,0.00141801],"study_design_scores_gemma":[0.002318304,0.0006321328,0.0009257197,0.00007396071,0.00004007239,0.0001425398,0.0001753151,0.00001825491,0.9651444,0.0006595481,0.02969606,0.0001736858],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962872,0.0005313358,0.000524666,0.001330996,0.00004817689,0.0003697664,0.00004204227,0.00001721138,0.0008486321],"genre_scores_gemma":[0.9973224,0.0001822002,0.000375179,0.0003296715,0.001186602,0.00004412459,0.0001145058,0.00001415793,0.0004311659],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03011451,"threshold_uncertainty_score":0.4793668,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03694237089834256,"score_gpt":0.295747368920857,"score_spread":0.2588049980225144,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}