{"id":"W2118449713","doi":"10.1074/jbc.m402897200","title":"Intracellular Delivery of Phosphatidylinositol (3,4,5)-Trisphosphate Causes Incorporation of Glucose Transporter 4 into the Plasma Membrane of Muscle and Fat Cells without Increasing Glucose Uptake","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University; Hospital for Sick Children","funders":"Banting and Best Diabetes Centre, University of Toronto; Canadian Institutes of Health Research; University of California, San Diego; Hospital for Sick Children; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; Novo Nordisk; Canadian Diabetes Association; European Foundation for the Study of Diabetes; National Institutes of Health","keywords":"GLUT4; Glucose transporter; Glucose uptake; Phosphatidylinositol; Intracellular; Protein kinase B; Chromosomal translocation; Cell membrane; Biology; Chemistry; Internal medicine; Cell biology; Cell; Endocrinology; Phosphorylation; Biochemistry; Insulin; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001455128,0.0004394865,0.0003381001,0.0002247586,0.0002438668,0.0003465021,0.0003529749,0.0004040857,0.001470851],"category_scores_gemma":[0.0001047689,0.0002519306,0.0004576386,0.0002851893,0.0003442393,0.0002900737,0.0002916185,0.0008980819,0.0005715322],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007165205,"about_ca_system_score_gemma":0.0004309067,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001494751,"about_ca_topic_score_gemma":0.001748936,"domain_scores_codex":[0.9997694,0.00002439846,0.00002213196,0.00006171176,0.00005185438,0.00007045493],"domain_scores_gemma":[0.9998912,0.00002190135,0.00002587372,0.00001817332,0.00001091808,0.00003193074],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001378815,0.00002005362,0.00002696544,0.00001605012,0.000002903532,0.00002594839,0.000007595818,0.00002401908,0.9993629,0.00006317115,0.00001564019,0.000297071],"study_design_scores_gemma":[0.00002029722,0.0001402202,0.0007133468,0.000001834657,0.000009480204,0.00005423661,0.00001009779,0.0002821162,0.9979628,0.00002152203,0.0007814452,0.000002455019],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903615,0.001157219,0.004966505,0.0001803468,0.0001032309,0.00006133135,0.0006532508,0.0001677498,0.002348984],"genre_scores_gemma":[0.9781559,0.001703779,0.009233776,0.000148268,0.00002631696,0.0001588933,0.001526754,0.0001225703,0.008923629],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001494751,"threshold_uncertainty_score":0.005198777,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01041021579503768,"score_gpt":0.2191706179008245,"score_spread":0.2087604021057868,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}