{"id":"W2118471443","doi":"10.1139/y05-090","title":"The latch-bridge hypothesis of smooth muscle contraction","year":2005,"lang":"en","type":"review","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Cardiomyopathy and Myosin Studies","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute","keywords":"Phosphorylation; Dephosphorylation; Myosin; Cooperativity; Biophysics; Chemistry; Muscle contraction; Actin; Myofilament; Phosphatase; Biochemistry; Biology; Anatomy","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003839287,0.0001966421,0.00150929,0.0001965381,0.0001934694,0.000004166141,0.0001180768,0.0002434386,0.0001968517],"category_scores_gemma":[0.00007949749,0.0001234263,0.0004410296,0.0001049411,0.0005400529,0.0000326755,0.00001410201,0.0005955644,0.000005309702],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009077457,"about_ca_system_score_gemma":0.001276682,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001694879,"about_ca_topic_score_gemma":0.0003501848,"domain_scores_codex":[0.9987102,0.000275491,0.000550591,0.0001310989,0.00005490259,0.0002777592],"domain_scores_gemma":[0.998058,0.0007910593,0.0006009443,0.0001042979,0.0001704194,0.0002753172],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005907998,0.00001801286,0.000008176443,0.001457935,0.0009646438,0.0001045882,0.00008994558,5.953608e-7,0.0008102193,0.00004397463,0.01269969,0.9837431],"study_design_scores_gemma":[0.0005170442,0.0001919232,0.002356001,0.000511512,0.00294936,0.0006478569,0.00002430638,3.292672e-7,0.00006087977,0.00006593603,0.9925834,0.00009146966],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003045611,0.9945329,9.516847e-7,0.0004593421,0.001357161,0.0002334069,0.00004782187,0.000002185905,0.0003206078],"genre_scores_gemma":[0.02444118,0.9736657,0.0000150307,0.0003068836,0.001427725,0.000006146311,0.00000376667,0.00001621021,0.0001174041],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9836517,"threshold_uncertainty_score":0.5033179,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0575236150179449,"score_gpt":0.3433441402209429,"score_spread":0.285820525202998,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}