{"id":"W2118508162","doi":"10.1038/cr.2008.67","title":"An EAL domain protein and cyclic AMP contribute to the interaction between the two quorum sensing systems in Escherichia coli","year":2008,"lang":"en","type":"article","venue":"Cell Research","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Chinese Academy of Sciences; Institute of Genetics; National Natural Science Foundation of China; Texas State University; Princeton University","keywords":"Autoinducer; Quorum sensing; Biology; Escherichia coli; Extracellular; Intracellular; Cell biology; Signal transduction; Mutation; Homoserine; Microbiology; Bacteria; Biochemistry; Genetics; Biofilm; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004211666,0.0002809906,0.0002745994,0.0002583316,0.000533878,0.0008716098,0.0003954809,0.0006346346,0.000935179],"category_scores_gemma":[0.0006590874,0.0002437094,0.0002445852,0.0001921861,0.0004432865,0.0004769417,0.0006086546,0.0007234917,0.00054183],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000649165,"about_ca_system_score_gemma":0.000305755,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007727429,"about_ca_topic_score_gemma":0.0006688935,"domain_scores_codex":[0.9996879,0.00007491258,0.0000158374,0.00003393241,0.0001111119,0.00007636336],"domain_scores_gemma":[0.9995946,0.0001506053,0.00006597459,0.00003339653,0.00005231821,0.0001030174],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001362784,0.00004832867,0.000720986,0.00002849924,0.000005630365,0.0001336588,0.00004372958,0.0001293229,0.9964314,0.0006303581,0.00006273299,0.001629219],"study_design_scores_gemma":[0.00004305448,0.0001137792,0.01574805,0.00001109595,0.00002270786,0.0005671293,0.000195533,0.006560136,0.9731855,0.000465322,0.003063446,0.00002418103],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947054,0.001022596,0.002497364,0.0002934249,0.00002510575,0.000007839467,0.0000409381,0.00002524498,0.001382204],"genre_scores_gemma":[0.9958345,0.000177823,0.002306318,0.0001285205,0.00001021511,0.00001004152,0.00009311028,0.00000889999,0.001430642],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000935179,"threshold_uncertainty_score":0.004710078,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03881903910163351,"score_gpt":0.3272132863950657,"score_spread":0.2883942472934322,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}