{"id":"W2118521074","doi":"10.1016/j.eururo.2013.09.005","title":"Efficacy and Safety of Abiraterone Acetate in an Elderly Patient Subgroup (Aged 75 and Older) with Metastatic Castration-resistant Prostate Cancer After Docetaxel-based Chemotherapy","year":2013,"lang":"en","type":"article","venue":"European Urology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":86,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency; Université de Montréal","funders":"","keywords":"Medicine; Abiraterone acetate; Docetaxel; Prostate cancer; Hazard ratio; Internal medicine; Clinical endpoint; Proportional hazards model; Urology; Prednisone; Placebo; Post-hoc analysis; Confidence interval; Androgen deprivation therapy; Chemotherapy; Oncology; Cancer; Randomized controlled trial; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004300093,0.00028916,0.001010619,0.0004129799,0.0003313481,0.0005631021,0.0001506757,0.0002130606,0.0006129856],"category_scores_gemma":[0.0009726982,0.0001148556,0.0007148682,0.0005450947,0.0002167709,0.0003144209,0.0002044566,0.0003620012,0.0001117269],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004173259,"about_ca_system_score_gemma":0.000470418,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002538709,"about_ca_topic_score_gemma":0.005137393,"domain_scores_codex":[0.9998057,0.00004848041,0.00002988872,0.00003331664,0.00003999914,0.00004252684],"domain_scores_gemma":[0.9995663,0.0001075799,0.0001316731,0.00002270838,0.00003118165,0.0001405417],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.06560086,0.001021358,0.871479,0.0001330378,0.001063173,0.000898187,0.0003655318,0.0008857672,0.008568816,0.00009141699,0.0004673103,0.04942551],"study_design_scores_gemma":[0.001801425,0.007678032,0.9847809,0.00002918461,0.001248759,0.001078756,0.0003930938,0.001078238,0.000754431,0.0001437955,0.0009863268,0.0000270925],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988081,0.0007809023,0.0000231794,0.00004537679,0.000008237808,0.0000077425,0.00008842823,0.000002012914,0.0002360507],"genre_scores_gemma":[0.9993661,0.0003155725,0.00002831536,0.0000426774,0.0000251343,0.000004416378,0.0001273958,8.066019e-7,0.0000896477],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002538709,"threshold_uncertainty_score":0.005047798,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01238519206517748,"score_gpt":0.2647034834322848,"score_spread":0.2523182913671073,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}