{"id":"W2118540283","doi":"10.1128/mcb.01264-12","title":"Tyrosine Phosphorylation of the Rho Guanine Nucleotide Exchange Factor Trio Regulates Netrin-1/DCC-Mediated Cortical Axon Outgrowth","year":2012,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; McGill University Health Centre","keywords":"Netrin; Guanine nucleotide exchange factor; Biology; Axon guidance; Deleted in Colorectal Cancer; Growth cone; Cell biology; Neurite; Phosphorylation; Tyrosine phosphorylation; GTPase; RAC1; Axon; Nerve growth factor; Signal transduction; Receptor; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007888428,0.0003675651,0.0002102103,0.0002359477,0.0002038909,0.0003612167,0.0001958912,0.0001914561,0.0007827638],"category_scores_gemma":[0.00009196495,0.0001809066,0.0002251963,0.000134669,0.0002640802,0.0001918613,0.0003022654,0.000466534,0.0004839974],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005011688,"about_ca_system_score_gemma":0.0003666509,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001283824,"about_ca_topic_score_gemma":0.001955635,"domain_scores_codex":[0.9998888,0.00001035083,0.000008139102,0.00002591393,0.00002136077,0.00004556025],"domain_scores_gemma":[0.9998461,0.000007654085,0.00005245234,0.000007797074,0.00001149685,0.00007453247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009264116,0.00001471744,0.0002223726,0.00001900055,0.000002599231,0.00005123308,0.00000959318,0.00005145607,0.9990607,0.0000646668,0.00002658989,0.0003843599],"study_design_scores_gemma":[0.00002726602,0.0001292745,0.03881545,0.000009221949,0.00002810805,0.0003382004,0.00009171042,0.003383392,0.9553098,0.00007263025,0.001781289,0.00001360836],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966632,0.0008188828,0.0008695727,0.00006028831,0.00001438787,0.00001468045,0.0001939891,0.00004992017,0.001315093],"genre_scores_gemma":[0.9964237,0.0007509852,0.0004687822,0.00003428493,0.000004979044,0.00002487652,0.0002771771,0.00002036692,0.001994844],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001283824,"threshold_uncertainty_score":0.003636241,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02301972201222758,"score_gpt":0.2395460299132347,"score_spread":0.2165263079010072,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}