{"id":"W2118548448","doi":"10.1038/35017046","title":"LET-413 is a basolateral protein required for the assembly of adherens junctions in Caenorhabditis elegans","year":2000,"lang":"en","type":"article","venue":"Nature Cell Biology","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":185,"is_retracted":false,"has_abstract":false,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Adherens junction; Cell biology; PDZ domain; Caenorhabditis elegans; Biology; Cell polarity; Epithelial polarity; CDC42; Signal transducing adaptor protein; Tight junction; Cell junction; Cytoskeleton; GTPase; Cadherin; Chemistry; Epithelium; Gene; Cell; Genetics; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000140623,0.0004587915,0.0004095009,0.0003760074,0.001087121,0.0007563762,0.0003934669,0.0008052848,0.001105401],"category_scores_gemma":[0.0002322599,0.0004798554,0.0003436967,0.000191666,0.0006295129,0.0004241333,0.0005851118,0.00107169,0.00152102],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007705384,"about_ca_system_score_gemma":0.000520688,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002075277,"about_ca_topic_score_gemma":0.003472162,"domain_scores_codex":[0.9997777,0.00001442815,0.00002276701,0.00004818994,0.0001011347,0.00003570757],"domain_scores_gemma":[0.9996067,0.00004055426,0.0001185023,0.00004667477,0.00004460917,0.0001430756],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007113238,0.000006865927,0.0001711333,0.000011697,0.000002446588,0.0001580521,0.00001019959,0.00006758246,0.9989005,0.0001279514,0.00005479011,0.0004175373],"study_design_scores_gemma":[0.00001789596,0.00003931995,0.007773828,0.000007009568,0.00001693409,0.0006074804,0.00005781775,0.002241233,0.9863518,0.0001764917,0.002691687,0.00001839365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906067,0.000697866,0.005912364,0.0001661401,0.00007478645,0.00001181976,0.0004770283,0.0004045941,0.001648733],"genre_scores_gemma":[0.9919298,0.0002232614,0.003411318,0.00009596624,0.000008969642,0.00001311345,0.000731598,0.000163404,0.003422627],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002075277,"threshold_uncertainty_score":0.005590677,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006905167199085899,"score_gpt":0.2400411822636144,"score_spread":0.2331360150645285,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}