{"id":"W2118583673","doi":"10.1186/1755-1536-3-8","title":"Towards an anti-fibrotic therapy for scleroderma: targeting myofibroblast differentiation and recruitment","year":2010,"lang":"en","type":"article","venue":"Fibrogenesis & Tissue Repair","topic":"Connective Tissue Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Arthritis Society","keywords":"Myofibroblast; Fibrosis; CTGF; Extracellular matrix; Medicine; Pericyte; Growth factor; Fibroblast; Connective tissue; Wound healing; Transforming growth factor; Pathology; Cell biology; Platelet-derived growth factor receptor; Cancer research; Immunology; Biology; Internal medicine; Endothelial stem cell; Receptor; Cell culture; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009149523,0.000729398,0.001059481,0.0009531866,0.0002904002,0.001220368,0.0007773826,0.001519868,0.002908531],"category_scores_gemma":[0.0004540323,0.0002494355,0.0005479445,0.0005533767,0.000543991,0.001513135,0.0006228941,0.00229997,0.001864602],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005632618,"about_ca_system_score_gemma":0.0006282632,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002441704,"about_ca_topic_score_gemma":0.0005628158,"domain_scores_codex":[0.999668,0.00007511082,0.00004197813,0.00004456361,0.0001274567,0.00004285292],"domain_scores_gemma":[0.9997597,0.00006010717,0.00004073988,0.000008260517,0.00009351037,0.00003755102],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003780195,0.0002558603,0.0005868744,0.02911414,0.0002628544,0.0009502893,0.0005375441,0.0008301331,0.1989831,0.01012558,0.05929839,0.6986774],"study_design_scores_gemma":[0.00005172381,0.0006529159,0.00116201,0.001931862,0.0002455373,0.002148497,0.0001444418,0.0003361477,0.01811935,0.003348673,0.9718308,0.00002805612],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.001653588,0.989287,0.002237414,0.002519255,0.002417585,0.00004346281,0.00003404827,0.00006114602,0.001746474],"genre_scores_gemma":[0.006838491,0.9806208,0.003063811,0.002561661,0.002109405,0.00007000117,0.00009989817,0.00002433445,0.004611479],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002908531,"threshold_uncertainty_score":0.009729981,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04127165831074775,"score_gpt":0.3267468536509936,"score_spread":0.2854751953402458,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}