{"id":"W2118613970","doi":"10.1212/01.wnl.0000343512.36654.41","title":"A new sensitive imaging biomarker for Parkinson disease?","year":2009,"lang":"en","type":"letter","venue":"Neurology","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"","keywords":"Pars compacta; Substantia nigra; Biomarker; Disease; Neuroimaging; Neuroscience; Parkinson's disease; Medicine; Neuromelanin; Dopaminergic; Diffusion MRI; Midbrain; Pathology; Magnetic resonance imaging; Psychology; Dopamine; Radiology; Biology; Central nervous system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002298148,0.0009814462,0.002435766,0.001054089,0.001117171,0.001530555,0.001157827,0.01397413,0.002424293],"category_scores_gemma":[0.01023474,0.000431608,0.0006967902,0.0006596774,0.002899328,0.004209943,0.0006648109,0.01261624,0.002974317],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002328541,"about_ca_system_score_gemma":0.0008653756,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007615545,"about_ca_topic_score_gemma":0.001192917,"domain_scores_codex":[0.9979051,0.0006575309,0.0003094012,0.0002818993,0.0006723405,0.000173637],"domain_scores_gemma":[0.9961746,0.002157028,0.0002654892,0.0001769958,0.0008492252,0.0003766277],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007843597,0.0004644433,0.01561756,0.001383961,0.000175871,0.06335302,0.0005332211,0.0003845315,0.01119336,0.02041687,0.5808929,0.3048],"study_design_scores_gemma":[0.0003653303,0.0008417708,0.006430709,0.001518115,0.0001556623,0.1123417,0.0007811587,0.001736709,0.004242512,0.04703132,0.8243976,0.0001572879],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.005081769,0.06598055,0.002988285,0.8990157,0.0199341,0.00008185302,0.00008343607,0.0001012048,0.006733081],"genre_scores_gemma":[0.07977968,0.06703889,0.009182181,0.6940094,0.1352392,0.0002972508,0.0002059985,0.0000637847,0.01418363],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01397413,"threshold_uncertainty_score":0.01689488,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01857487192161128,"score_gpt":0.2702514665663884,"score_spread":0.2516765946447771,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}