{"id":"W2118634531","doi":"10.1128/jvi.74.24.11504-11510.2000","title":"Herpes Simplex Virus Type 1 ICP4 Promotes Transcription Preinitiation Complex Formation by Enhancing the Binding of TFIID to DNA","year":2000,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":84,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Medical Research Council; National Institutes of Health; Medical Research Council Canada","keywords":"Transcription factor II A; TATA box; TAF1; Transcription factor II D; Transcription preinitiation complex; Biology; Transcription factor II B; Molecular biology; TAF2; Promoter; Cell biology; Genetics; Gene; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002965056,0.00008604916,0.0002356779,0.0001273611,0.00009152869,0.00001156464,0.000050736,0.00007406934,0.0007490906],"category_scores_gemma":[0.00005158587,0.00005728493,0.00007884645,0.000178122,0.00003168084,0.000214022,0.000004290876,0.0001127692,0.00004232545],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007206841,"about_ca_system_score_gemma":0.00004719604,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003468225,"about_ca_topic_score_gemma":0.00004103169,"domain_scores_codex":[0.9990625,0.00009833001,0.0004845344,0.00006800348,0.0001512804,0.0001353251],"domain_scores_gemma":[0.9994324,0.00006479186,0.0002245978,0.00009142903,0.0001271843,0.00005956964],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005869696,0.0003464122,0.0002314169,0.00002957022,0.0001532347,0.00000738369,0.001200711,0.00009799602,0.7919849,0.00002619284,0.0008845624,0.2044507],"study_design_scores_gemma":[0.003531521,0.005909891,0.02043482,0.0001693898,0.0005291362,0.0007043005,0.0002855086,0.0007253701,0.8032987,0.000408201,0.16384,0.0001631818],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958879,0.00008637295,0.001747521,0.001228794,0.0001030411,0.0002289071,0.000009381312,0.000009014261,0.0006990228],"genre_scores_gemma":[0.9988753,0.0001216261,0.0004216385,0.0003793257,0.0000974055,0.000003972732,0.00001599975,0.000009620702,0.00007514831],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2042875,"threshold_uncertainty_score":0.8202016,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0314079839828974,"score_gpt":0.3059513832780003,"score_spread":0.2745433992951029,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}