{"id":"W2118634531","doi":"10.1128/jvi.74.24.11504-11510.2000","title":"Herpes Simplex Virus Type 1 ICP4 Promotes Transcription Preinitiation Complex Formation by Enhancing the Binding of TFIID to DNA","year":2000,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":84,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Medical Research Council; National Institutes of Health; Medical Research Council Canada","keywords":"Transcription factor II A; TATA box; TAF1; Transcription factor II D; Transcription preinitiation complex; Biology; Transcription factor II B; Molecular biology; TAF2; Promoter; Cell biology; Genetics; Gene; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003475472,0.0006994122,0.0004882328,0.0007383797,0.0002597938,0.0004751114,0.0003599466,0.0002531426,0.001954573],"category_scores_gemma":[0.0004387474,0.000334554,0.0005159545,0.0002686787,0.0004318455,0.0002903186,0.0006638789,0.0009185773,0.000687324],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008751879,"about_ca_system_score_gemma":0.0004992571,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001096606,"about_ca_topic_score_gemma":0.0007573644,"domain_scores_codex":[0.9996129,0.00007128406,0.00003232415,0.00008044133,0.0001193255,0.00008388677],"domain_scores_gemma":[0.9997799,0.00004828725,0.00004684935,0.0000277316,0.00004157817,0.00005568912],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009150568,0.00002491403,0.0002317001,0.00004479827,0.000007715709,0.0000313926,0.00002979081,0.00005373578,0.9979926,0.0001233559,0.00006358344,0.001304878],"study_design_scores_gemma":[0.0000127775,0.00006808345,0.00183678,0.000005614753,0.00000920596,0.00008200106,0.00001445177,0.0008070247,0.9937879,0.0000839704,0.003287159,0.000004977096],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9728133,0.002968369,0.02039233,0.0001221794,0.0001447274,0.00009534388,0.0003596398,0.0004244084,0.002679709],"genre_scores_gemma":[0.9710799,0.001501586,0.01966174,0.0000559451,0.00005448973,0.00009039519,0.001165483,0.0001272614,0.006263093],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001954573,"threshold_uncertainty_score":0.006538749,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0314079839828974,"score_gpt":0.3059513832780003,"score_spread":0.2745433992951029,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}