{"id":"W2118694630","doi":"10.1128/jvi.00232-15","title":"Influenza A Virus Panhandle Structure Is Directly Involved in RIG-I Activation and Interferon Induction","year":2015,"lang":"en","type":"article","venue":"Journal of Virology","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":111,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"Biology; RIG-I; RNA; Transcription (linguistics); Viral replication; Interferon; Influenza A virus; Virology; Virus; Gene; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003556576,0.0001308922,0.0003311296,0.0003644387,0.00003644668,0.00001237084,0.0001208472,0.0003467983,0.0001705261],"category_scores_gemma":[0.0002279252,0.0001032867,0.00004615081,0.0001003982,0.0001421877,0.0002527635,0.0000565513,0.0005859758,0.00002121177],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008866868,"about_ca_system_score_gemma":0.000090163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001119101,"about_ca_topic_score_gemma":0.00008553757,"domain_scores_codex":[0.9988131,0.0003871928,0.0004449067,0.0001262844,0.00003607083,0.0001924778],"domain_scores_gemma":[0.9993401,0.00008428532,0.000313649,0.0001041225,0.0001280973,0.00002971582],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005018993,0.0000749985,0.004287742,0.000005395576,0.0000946589,0.000005441846,0.002518458,0.00000503933,0.9818571,0.0000436126,0.001713259,0.00437537],"study_design_scores_gemma":[0.003902416,0.003023851,0.0376644,0.00005798173,0.00003313109,0.0005157837,0.0009841206,0.000006649249,0.9210722,0.0009180706,0.03167826,0.0001430912],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958822,0.002629376,0.00007234387,0.0004726838,0.0007842632,0.00007063819,0.000005551983,0.000007780955,0.00007512652],"genre_scores_gemma":[0.9988974,0.0001046396,0.00003950307,0.0007525095,0.0000530553,0.000001476391,0.000004066757,0.000009607758,0.0001377626],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06078479,"threshold_uncertainty_score":0.4211909,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03168966961906999,"score_gpt":0.2827246108566988,"score_spread":0.2510349412376288,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}