{"id":"W2118837528","doi":"10.1158/1078-0432.ccr-10-0395","title":"HDAC5 and HDAC9 in Medulloblastoma: Novel Markers for Risk Stratification and Role in Tumor Cell Growth","year":2010,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":193,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"Bundesministerium für Bildung und Forschung","keywords":"Medulloblastoma; Histone deacetylase 5; Gene knockdown; Cancer research; Biology; Histone deacetylase; Immunology; Oncology; Medicine; Cell culture; Histone; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002357116,0.0005039061,0.0003626279,0.0007817362,0.0001875008,0.0004465079,0.0002320654,0.0002163952,0.0008565615],"category_scores_gemma":[0.0002182901,0.0001456303,0.0003347375,0.0005238261,0.0002404775,0.0002245516,0.0001916468,0.0003533081,0.0003184713],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007559026,"about_ca_system_score_gemma":0.0002949588,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002709071,"about_ca_topic_score_gemma":0.004187731,"domain_scores_codex":[0.9998518,0.00001972343,0.00001449913,0.00004283233,0.00004560834,0.00002537397],"domain_scores_gemma":[0.9998678,0.0000141869,0.00006457908,0.000007526246,0.00002153409,0.00002430506],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001748262,0.00008904431,0.208874,0.0006406644,0.0002568563,0.0005684859,0.0001181932,0.0006636757,0.7124329,0.0003916419,0.0009136571,0.07330257],"study_design_scores_gemma":[0.00004319751,0.0004945075,0.7655903,0.00006946595,0.0003626309,0.002624456,0.0001643578,0.003504522,0.2155324,0.0003609761,0.01122721,0.00002601921],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9394894,0.0479015,0.007654134,0.0003295195,0.00006895207,0.00007890158,0.001912051,0.0001833194,0.002382174],"genre_scores_gemma":[0.9875557,0.006160417,0.003944261,0.00004241429,0.00004690255,0.00002226587,0.001086128,0.00001004885,0.001131945],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002709071,"threshold_uncertainty_score":0.005484521,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04207828477692169,"score_gpt":0.4311376314385805,"score_spread":0.3890593466616588,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}