{"id":"W2118846800","doi":"10.1002/art.20676","title":"Digital ulcers in systemic sclerosis: Prevention by treatment with bosentan, an oral endothelin receptor antagonist","year":2004,"lang":"en","type":"article","venue":"Arthritis & Rheumatism","topic":"Systemic Sclerosis and Related Diseases","field":"Medicine","cited_by":726,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Western University","funders":"National Center for Research Resources","keywords":"Bosentan; Medicine; Internal medicine; Endothelin receptor antagonist; Scleroderma (fungus); Placebo; Endothelin receptor; Gastroenterology; Clinical endpoint; Surgery; Randomized controlled trial; Receptor; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001175737,0.0002971494,0.0005358604,0.0001258294,0.0001171843,0.0001359562,0.00008386459,0.0001429326,0.0001268635],"category_scores_gemma":[0.00001647101,0.0002307311,0.0001205232,0.0002126903,0.0001124923,0.0004585342,0.00001430796,0.000117007,0.0001483944],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005072063,"about_ca_system_score_gemma":0.0002004191,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009457787,"about_ca_topic_score_gemma":0.0003593925,"domain_scores_codex":[0.9981176,0.00007291979,0.00060348,0.0004719366,0.0003527237,0.0003813709],"domain_scores_gemma":[0.9991142,0.00002386434,0.0001714281,0.0003526951,0.00004903935,0.0002887493],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0007116806,0.003409649,0.04958811,0.0001544857,0.0004220968,0.0001393519,0.002352577,0.00009552521,0.06860068,0.0002704513,0.0009291185,0.8733262],"study_design_scores_gemma":[0.253148,0.04092852,0.09850727,0.467586,0.0010074,0.009580377,0.03735141,0.0003980586,0.0822456,0.0008215462,0.003596393,0.004829397],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9681627,0.02937008,0.00009441358,0.0002485709,0.0001879368,0.001042313,0.0002128049,0.0001573464,0.0005238699],"genre_scores_gemma":[0.9645447,0.03393632,0.0002577377,0.00006418268,0.00004028449,0.0001920152,0.000443088,0.00005525833,0.0004664093],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8684969,"threshold_uncertainty_score":0.9408941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01613395426366306,"score_gpt":0.24268793006937,"score_spread":0.226553975805707,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}