{"id":"W2118857462","doi":"10.1002/bit.22634","title":"Effect of cell lysates on retroviral transduction efficiency of cells in suspension culture","year":2009,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"","keywords":"Transduction (biophysics); Cell culture; Protamine sulfate; Lysis; Cell growth; Biology; Cell; Protamine; Cell biology; Tropism; Molecular biology; Chemistry; Biochemistry; Virology; Virus; Genetics; Heparin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001857372,0.0001049925,0.0001479118,0.0001498356,0.0000146744,0.000001694334,0.00009524896,0.0003265972,0.000001695632],"category_scores_gemma":[0.000013529,0.00008603305,0.0000379541,0.0001705026,0.00007559753,0.000001921889,0.00001566654,0.000140224,4.888854e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006693771,"about_ca_system_score_gemma":0.000007159004,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002398908,"about_ca_topic_score_gemma":0.000003325806,"domain_scores_codex":[0.9994456,0.00003120613,0.0001309113,0.0001835945,0.00006002798,0.000148677],"domain_scores_gemma":[0.9997659,0.000007880307,0.00003203145,0.0001634361,0.00001316528,0.00001756823],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008853482,0.00004510907,0.00006152374,0.00004563161,0.000005869396,0.00000151606,0.00001906623,0.000311261,0.994271,0.0000154462,0.000005705919,0.004332555],"study_design_scores_gemma":[0.0005367232,0.01360873,0.0001477399,0.00002438048,0.000005347582,0.00000263415,0.00001217094,0.0002244864,0.9853107,0.000004533753,0.00004734314,0.00007515706],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986207,0.0009690117,0.0001325034,0.0000678381,0.00003617693,0.0001318843,0.000003645208,0.00001448859,0.00002375943],"genre_scores_gemma":[0.9991803,0.0006496262,0.0001164257,0.000007445678,0.00001544552,0.000001629413,0.00000685028,0.000006121822,0.00001617253],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01356362,"threshold_uncertainty_score":0.3508326,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003861181627338392,"score_gpt":0.2318275431811587,"score_spread":0.2279663615538203,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}