{"id":"W2118857462","doi":"10.1002/bit.22634","title":"Effect of cell lysates on retroviral transduction efficiency of cells in suspension culture","year":2009,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"","keywords":"Transduction (biophysics); Cell culture; Protamine sulfate; Lysis; Cell growth; Biology; Cell; Protamine; Cell biology; Tropism; Molecular biology; Chemistry; Biochemistry; Virology; Virus; Genetics; Heparin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001206772,0.0007938645,0.0007275181,0.0003240661,0.0001627864,0.000806927,0.0003244167,0.0003739218,0.001284285],"category_scores_gemma":[0.001106298,0.0002945558,0.0002781354,0.0002330192,0.0002726257,0.0003467488,0.0004672984,0.001045514,0.0007818614],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003711301,"about_ca_system_score_gemma":0.0002499917,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005621358,"about_ca_topic_score_gemma":0.0006412666,"domain_scores_codex":[0.9984735,0.0005697819,0.0001966303,0.0002254646,0.0004102432,0.0001244102],"domain_scores_gemma":[0.9984506,0.0009715759,0.0001501871,0.0001636022,0.0001762199,0.0000876845],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000116103,0.00007094787,0.0001980949,0.00003561976,0.000009626027,0.00002001413,0.00005667645,0.00008177217,0.9974825,0.00005744859,0.00004667016,0.00182466],"study_design_scores_gemma":[0.000005168631,0.0003368324,0.0008091223,0.000004681803,0.000009878621,0.00002990029,0.00001178877,0.0004243745,0.9977009,0.00001058087,0.0006527973,0.000004043286],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9839858,0.002505071,0.009378728,0.0001023459,0.00009026581,0.0001371829,0.0006012102,0.0002429248,0.002956474],"genre_scores_gemma":[0.9784542,0.001922227,0.01194867,0.000129239,0.00003664013,0.0001500131,0.001806957,0.0001705681,0.005381633],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001284285,"threshold_uncertainty_score":0.006382108,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003861181627338392,"score_gpt":0.2318275431811587,"score_spread":0.2279663615538203,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}