{"id":"W2118901204","doi":"10.1074/jbc.m111404200","title":"Activation of Smooth Muscle Myosin Light Chain Kinase by Calmodulin","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Institutes of Health Research","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Myosin light-chain kinase; Calmodulin; Myosin; Biophysics; Mutant; Biochemistry; Cell biology; Muscle contraction; Contraction (grammar); Chemistry; Biology; Enzyme; Anatomy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009025689,0.0002244677,0.0001908348,0.0001029206,0.0001293367,0.0001656604,0.0001790676,0.0001958221,0.0008894175],"category_scores_gemma":[0.0001088,0.0001373265,0.0002846417,0.0000948938,0.0001802487,0.0001359816,0.0002212636,0.0003390518,0.0002995792],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003355254,"about_ca_system_score_gemma":0.0001478903,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006452912,"about_ca_topic_score_gemma":0.0009862389,"domain_scores_codex":[0.9999157,0.0000105202,0.00000521066,0.00002381317,0.00002297116,0.00002171173],"domain_scores_gemma":[0.9999522,0.000006561439,0.00001631838,0.000006024234,0.000006074412,0.00001281866],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002490286,0.000004065733,0.0002264698,0.00001522547,0.000002992511,0.00001767779,0.000003624345,0.00002193308,0.9992191,0.0000349558,0.00001364131,0.0004154975],"study_design_scores_gemma":[0.00003565774,0.0001630211,0.01413292,0.000006763711,0.00001210219,0.0002775787,0.00001609992,0.001829186,0.9803119,0.0001075808,0.003102059,0.00000510617],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960282,0.001120853,0.001921754,0.00004783363,0.00001774546,0.00001765636,0.0001412134,0.00002839142,0.0006763943],"genre_scores_gemma":[0.9953331,0.0006534769,0.002370146,0.00003067097,0.000006094188,0.00001942945,0.0004760089,0.000008307039,0.001102774],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008894175,"threshold_uncertainty_score":0.002975404,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01675749547922629,"score_gpt":0.2301563939677909,"score_spread":0.2133988984885646,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}