{"id":"W2118947150","doi":"10.1128/mcb.01257-12","title":"Active Stabilization of Human Endothelial Nitric Oxide Synthase mRNA by hnRNP E1 Protects against Antisense RNA and MicroRNAs","year":2013,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Canadian Institutes of Health Research","keywords":"Enos; Biology; Messenger RNA; Gene knockdown; Three prime untranslated region; RNA; Untranslated region; Molecular biology; Ribonucleoprotein; Small interfering RNA; RNA-binding protein; microRNA; Cell biology; RNA Helicase A; Nitric oxide synthase; Biochemistry; Nitric oxide; Helicase; Gene; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002321585,0.0003180826,0.0002606875,0.000112459,0.0001306133,0.0001655389,0.0001418724,0.0002137646,0.0005659506],"category_scores_gemma":[0.0002164633,0.0001580385,0.000242732,0.00006511442,0.0001758475,0.0001400521,0.0001647442,0.0003081376,0.0001753549],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001597012,"about_ca_system_score_gemma":0.000162052,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000307746,"about_ca_topic_score_gemma":0.000423815,"domain_scores_codex":[0.999841,0.00003266267,0.00001882433,0.0000522161,0.00003031359,0.00002497874],"domain_scores_gemma":[0.9998835,0.00002390898,0.00004179833,0.00001609999,0.00001552248,0.00001905955],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007586483,0.00001464181,0.00009406111,0.00002422657,0.000006177836,0.00001861949,0.000009709687,0.00004322186,0.9985826,0.00004553833,0.00001997388,0.001065338],"study_design_scores_gemma":[0.00001290049,0.0003437901,0.004056296,0.000005215064,0.00001751795,0.0001547692,0.00001103169,0.0007883766,0.9933004,0.00003804919,0.001267126,0.000004529435],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898456,0.003546741,0.005482994,0.00007453767,0.00004910972,0.00002507856,0.0001356677,0.00007869084,0.0007615102],"genre_scores_gemma":[0.9934596,0.001142684,0.002993417,0.0001072383,0.00001686964,0.00004193394,0.0004336782,0.00001810329,0.00178653],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005659506,"threshold_uncertainty_score":0.001893282,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006045185840334611,"score_gpt":0.2329181518421314,"score_spread":0.2268729660017968,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}