{"id":"W2118947150","doi":"10.1128/mcb.01257-12","title":"Active Stabilization of Human Endothelial Nitric Oxide Synthase mRNA by hnRNP E1 Protects against Antisense RNA and MicroRNAs","year":2013,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Canadian Institutes of Health Research","keywords":"Enos; Biology; Messenger RNA; Gene knockdown; Three prime untranslated region; RNA; Untranslated region; Molecular biology; Ribonucleoprotein; Small interfering RNA; RNA-binding protein; microRNA; Cell biology; RNA Helicase A; Nitric oxide synthase; Biochemistry; Nitric oxide; Helicase; Gene; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001477622,0.0002004824,0.0002408334,0.0000886079,0.0001128741,0.0000279739,0.0001216499,0.0002254382,0.00001426685],"category_scores_gemma":[0.0001063658,0.0001824087,0.0000669744,0.0000908871,0.0002771951,0.000007917268,0.000145393,0.0001270982,0.00000309254],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009834929,"about_ca_system_score_gemma":0.00003688217,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002748247,"about_ca_topic_score_gemma":0.000007165806,"domain_scores_codex":[0.9986787,0.0002076238,0.0002377839,0.0004423819,0.00008892929,0.0003445901],"domain_scores_gemma":[0.9993409,0.00001512582,0.0001127846,0.0002594276,0.0001224168,0.0001493278],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005742412,0.00006079681,0.0007144725,0.00004334646,0.00006363013,0.00001111764,0.00001820015,0.000001595501,0.9948193,0.00006891762,0.00008750526,0.004053727],"study_design_scores_gemma":[0.0007840911,0.0003990677,0.0003188321,0.00001375104,0.00001269327,0.00001117955,0.00006929662,0.00007043963,0.9974213,0.0001530437,0.0005519947,0.0001943694],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936687,0.002240122,0.003146502,0.00004996621,0.00001643858,0.0005692819,0.00005727549,0.000009013723,0.0002426864],"genre_scores_gemma":[0.9987932,0.0003212168,0.0001965345,0.0001088933,0.00002929079,0.00004522018,0.0002707643,0.00002620396,0.0002086103],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005124552,"threshold_uncertainty_score":0.7438412,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006045185840334611,"score_gpt":0.2329181518421314,"score_spread":0.2268729660017968,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}