{"id":"W2118961010","doi":"10.1021/bi012038+","title":"Proximity of the Protein Moiety of a GPI-Anchored Protein to the Membrane Surface:  A FRET Study","year":2002,"lang":"en","type":"article","venue":"Biochemistry","topic":"Porphyrin Metabolism and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Förster resonance energy transfer; Lipid bilayer; Chemistry; Bilayer; Placental alkaline phosphatase; Biophysics; Membrane; Vesicle; Membrane protein; Protein–lipid interaction; Biochemistry; Moiety; Fluorescence; Alkaline phosphatase; Enzyme; Integral membrane protein; Stereochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002978593,0.0001973659,0.0002193291,0.000009797749,0.00007852848,0.00001110423,0.0006744392,0.0001411289,0.00005110339],"category_scores_gemma":[0.0002322497,0.000123181,0.0001589925,0.000240938,0.0001583171,0.000003117599,0.0002825684,0.0001230308,0.00000373039],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007061747,"about_ca_system_score_gemma":0.00006454777,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006188137,"about_ca_topic_score_gemma":0.00002263305,"domain_scores_codex":[0.9986693,0.00009680731,0.0003230874,0.0003709738,0.0003053739,0.0002344264],"domain_scores_gemma":[0.9985248,0.000005463009,0.0001890273,0.001090414,0.0001194764,0.00007084608],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006938093,0.000472341,0.001609989,0.00009516394,0.00007242593,4.245086e-7,0.0002139476,0.0000282926,0.995423,0.00000675889,0.001785274,0.0002229842],"study_design_scores_gemma":[0.0006448856,0.0001225931,0.001463725,0.00002934895,0.00002936006,0.00000182548,0.0003855595,0.00002129068,0.9951743,0.00001809577,0.001956877,0.0001520637],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959622,0.0009868832,0.00002317969,0.0004392691,0.00004153934,0.001647666,0.00007984052,0.000008721716,0.0008107212],"genre_scores_gemma":[0.9971457,0.00001247022,0.0002742279,0.00006816366,0.00008389546,0.0001449358,0.00001014017,0.00001836855,0.002242086],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001502731,"threshold_uncertainty_score":0.5023175,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008977632308639247,"score_gpt":0.2142978804271549,"score_spread":0.2053202481185157,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}