{"id":"W2118995187","doi":"10.1158/1078-0432.ccr-07-0618","title":"The Cancer/Testis Antigen Melanoma-Associated Antigen-A3/A6 Is a Novel Target of Fibroblast Growth Factor Receptor 2-IIIb through Histone H3 Modifications in Thyroid Cancer","year":2007,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; Immunovaccine (Canada); University Health Network","funders":"","keywords":"Cancer research; Chromatin immunoprecipitation; Biology; DNA methylation; Thyroid cancer; Molecular biology; Carcinogenesis; Epigenetics; FGF10; Fibroblast growth factor receptor 2; Cancer; Fibroblast growth factor; Gene expression; Promoter; Receptor; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007031755,0.0001825561,0.0001226722,0.0001327259,0.0002082166,0.0001568836,0.0001204817,0.0001610212,0.001065613],"category_scores_gemma":[0.00006320726,0.00008290069,0.0002534967,0.0001345161,0.0001349206,0.00006827524,0.00009443182,0.000260081,0.0002965386],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003429987,"about_ca_system_score_gemma":0.0002224853,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001402328,"about_ca_topic_score_gemma":0.002025445,"domain_scores_codex":[0.9999415,0.00000544794,0.000002700256,0.00001701466,0.00002218161,0.0000111755],"domain_scores_gemma":[0.9999557,0.000004536621,0.00001327999,0.000003217192,0.000006952746,0.00001642884],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005249485,0.000007743678,0.0005086118,0.00002156775,0.000003151722,0.00004877181,0.00000659489,0.00002915563,0.9983069,0.00004115346,0.00003116636,0.0009427467],"study_design_scores_gemma":[0.00002758644,0.0004244723,0.05871883,0.000007760829,0.00003816879,0.001195528,0.00004020888,0.001426284,0.932067,0.0001367934,0.005909452,0.00000778755],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913967,0.003123106,0.003096736,0.0001106983,0.00002603257,0.00003824861,0.0005190813,0.0001046004,0.001584824],"genre_scores_gemma":[0.9948736,0.0008436253,0.001619806,0.00004887549,0.000008698331,0.00001698687,0.0006626878,0.000008390206,0.00191733],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001402328,"threshold_uncertainty_score":0.003564835,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.138876037139448,"score_gpt":0.4830170187010986,"score_spread":0.3441409815616505,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}