{"id":"W2119018891","doi":"10.1093/annonc/mdi240","title":"Cyclophosphamide-methotrexate ‘metronomic’ chemotherapy for the palliative treatment of metastatic breast cancer. A comparative pharmacoeconomic evaluation","year":2005,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Cancer Treatment and Pharmacology","field":"Medicine","cited_by":108,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"National Cancer Institute; Associazione Italiana per la Ricerca sul Cancro; Oncosuisse; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Medicine; Cyclophosphamide; Metastatic breast cancer; Breast cancer; Oncology; Chemotherapy; Methotrexate; Internal medicine; Cancer; Nitrogen mustard; Clinical trial; Palliative care; Nursing","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004197042,0.0001897965,0.000797058,0.00009447632,0.00005177307,0.00000262864,0.0000848015,0.00005138414,0.001493279],"category_scores_gemma":[0.000008611605,0.0001286263,0.0002592485,0.0001089256,0.0001886186,0.00005825588,0.000009048304,0.00005278021,0.000008676243],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004716787,"about_ca_system_score_gemma":0.0006130148,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004381411,"about_ca_topic_score_gemma":0.0002355714,"domain_scores_codex":[0.9988152,0.0001570423,0.0004688383,0.0002301907,0.00009468175,0.0002339831],"domain_scores_gemma":[0.9979942,0.0009142449,0.0005170366,0.0001544149,0.0003492484,0.00007087309],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01089497,0.004273168,0.006186512,0.00005849321,0.006422814,0.000001562235,0.005227744,0.003545582,0.0103049,0.0001285754,0.009716036,0.9432396],"study_design_scores_gemma":[0.06622124,0.02012493,0.1776646,0.00006349286,0.006418958,0.00003405685,0.00114734,0.03675822,0.3885072,0.0004758511,0.3021877,0.0003964246],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9597232,0.009361029,0.0001095879,0.02666814,0.0002565542,0.002466947,0.0004111628,0.00001089762,0.0009924382],"genre_scores_gemma":[0.9852735,0.01033721,0.001170003,0.001479299,0.0002837836,0.001058328,0.00004857039,0.00001624176,0.0003330668],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9428432,"threshold_uncertainty_score":0.9994195,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2514763485373673,"score_gpt":0.5328897417986063,"score_spread":0.2814133932612389,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}