{"id":"W2119116563","doi":"10.1530/rep-06-0256","title":"Effects of cryopreservation on sperm quality, nuclear DNA integrity, in vitro fertilization, and in vitro embryo development in the mouse","year":2007,"lang":"en","type":"article","venue":"Reproduction","topic":"Sperm and Testicular Function","field":"Medicine","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Genome Prairie; Canadian Institutes of Health Research; Genome Canada; Ontario Genomics; Ontario Genomics Institute; Ontario Innovation Trust","keywords":"Cryoprotectant; Sperm; Cryopreservation; DNA fragmentation; Andrology; Raffinose; Sperm motility; Human fertilization; Biology; Blastocyst; Chemistry; Embryo; Biochemistry; Sucrose; Embryogenesis; Anatomy; Cell biology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002139546,0.0001304075,0.0002351702,0.0002902249,0.0000397808,0.00001331066,0.0000558526,0.0001077298,0.000004145175],"category_scores_gemma":[0.001241872,0.0001038588,0.00003043384,0.0005843166,0.00004312353,0.0001305005,0.00002561863,0.0002822503,0.000005280162],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001752984,"about_ca_system_score_gemma":0.0000379374,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002961993,"about_ca_topic_score_gemma":0.0001300533,"domain_scores_codex":[0.9983995,0.000146619,0.0004916671,0.0004259094,0.0003547067,0.0001816085],"domain_scores_gemma":[0.9992841,0.0001394834,0.0001130228,0.0003368781,0.00009288028,0.00003367515],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002004239,0.0006617273,0.01539053,0.0002803165,0.000008436668,0.00001458801,0.001506757,0.00002811661,0.9707816,0.0001678349,0.00006533397,0.009090492],"study_design_scores_gemma":[0.0009975655,0.0000652315,0.438078,0.0000768561,0.00001086583,0.00001683604,0.0002187122,0.00007973254,0.5599111,0.00007425882,0.0004022902,0.0000685444],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997531,0.0001523953,0.0001588598,0.0008908692,0.0001657936,0.0007378777,4.425824e-7,0.00003205318,0.0003307257],"genre_scores_gemma":[0.9988238,0.00004556018,0.000530813,0.0003069291,0.0001315433,0.00001596739,0.00004272984,0.00001758221,0.00008504895],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4226875,"threshold_uncertainty_score":0.423524,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02441527548830512,"score_gpt":0.2796901177935676,"score_spread":0.2552748423052625,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}