{"id":"W2119122462","doi":"10.1158/0008-5472.can-03-3780","title":"Loss of Tumorigenicity and Metastatic Potential in Carcinoma Cells Expressing the Extracellular Domain of the Type 1 Insulin-Like Growth Factor Receptor","year":2004,"lang":"en","type":"article","venue":"Cancer Research","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; McGill University; Immunovaccine (Canada)","funders":"National Cancer Institute; National Institutes of Health; McGill University Health Centre; McGill University","keywords":"Extracellular; Cancer research; Insulin-like growth factor; Carcinoma; Internal medicine; Endocrinology; Receptor; Growth factor; Biology; Medicine; Chemistry; Oncology; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008742719,0.0001821425,0.000417376,0.0002116704,0.0001584766,0.00002167674,0.0003669735,0.00009577036,0.00007634405],"category_scores_gemma":[0.0001836365,0.0001076018,0.0001119605,0.0009796098,0.0008162426,0.0001111039,0.0002080156,0.0007603446,0.000005216711],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002219554,"about_ca_system_score_gemma":0.0007363597,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002902424,"about_ca_topic_score_gemma":0.00007011546,"domain_scores_codex":[0.9973941,0.0003722101,0.0005079937,0.0003339948,0.0008996147,0.0004921107],"domain_scores_gemma":[0.9986318,0.0001432707,0.000149985,0.0004885956,0.0004427312,0.0001436598],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007033597,0.0004467937,0.03615154,0.0004387052,0.00007118039,0.00004423755,0.004033875,0.00002113843,0.9571633,0.000325345,0.000201333,0.0003991348],"study_design_scores_gemma":[0.005470345,0.0004384461,0.149972,0.0003686818,0.00005862523,0.00001586438,0.001514026,0.00002578277,0.8401875,0.001251304,0.0005229269,0.0001744705],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919607,0.005993217,0.0000485265,0.0007807983,0.0002951726,0.0007923375,0.00004719058,0.000007881029,0.00007416814],"genre_scores_gemma":[0.9987191,0.000715056,0.000233654,0.00004469899,0.00009399709,0.00003142574,0.000003878275,0.00003147947,0.0001267427],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1169758,"threshold_uncertainty_score":0.4387872,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04850953812163934,"score_gpt":0.3243512795858223,"score_spread":0.2758417414641829,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}