{"id":"W2119129864","doi":"10.2337/db09-0165","title":"The microRNA Signature in Response to Insulin Reveals Its Implication in the Transcriptional Action of Insulin in Human Skeletal Muscle and the Role of a Sterol Regulatory Element–Binding Protein-1c/Myocyte Enhancer Factor 2C Pathway","year":2009,"lang":"en","type":"article","venue":"Diabetes","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":142,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute","funders":"Institut National de la Recherche Agronomique; Institut National de la Santé et de la Recherche Médicale","keywords":"Insulin; microRNA; Skeletal muscle; Action (physics); Biology; Myocyte; Human insulin; Cell biology; Internal medicine; Endocrinology; Gene; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001747977,0.000266989,0.0003206414,0.0002776207,0.0001237208,0.0002651529,0.0001006006,0.0002767549,0.001279163],"category_scores_gemma":[0.0002650392,0.0002151672,0.0003757145,0.0002507343,0.0001447953,0.00009972374,0.0001504655,0.0002950674,0.0004788341],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001356761,"about_ca_system_score_gemma":0.0001276076,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001832594,"about_ca_topic_score_gemma":0.0002502376,"domain_scores_codex":[0.9998125,0.00002730406,0.00001693186,0.00007844026,0.00004101027,0.000023841],"domain_scores_gemma":[0.9998773,0.00002558251,0.00004068026,0.00001039146,0.00002439388,0.00002165133],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003314845,0.00002013262,0.002652727,0.00004682666,0.00001552007,0.0001284009,0.00002486506,0.0000289764,0.9947962,0.00003220535,0.00004065275,0.001882027],"study_design_scores_gemma":[0.00008028902,0.0008329058,0.3382381,0.00003679213,0.0001872595,0.003553912,0.0001085193,0.002771819,0.6499282,0.0001529162,0.004086789,0.00002249903],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926029,0.00243637,0.003172335,0.00008103828,0.00004176438,0.00003179051,0.0005745944,0.00006155105,0.0009976325],"genre_scores_gemma":[0.9910309,0.0006938765,0.005436629,0.0001122286,0.0000251733,0.00007318303,0.000956682,0.00002770056,0.001643658],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001279163,"threshold_uncertainty_score":0.004279256,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007459179024292759,"score_gpt":0.2446463651242553,"score_spread":0.2371871860999625,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}