{"id":"W2119167266","doi":"10.1172/jci32567","title":"TNF-α is critical for antitumor but not antiviral T cell immunity in mice","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":222,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto; Ontario Institute for Cancer Research","funders":"National Cancer Institute; University of Toronto; Terry Fox Foundation; Campbell Family Institute for Breast Cancer Research","keywords":"Tumor necrosis factor alpha; Immunology; Immune system; Immunity; Inflammation; TLR2; Cytokine; Priming (agriculture); T cell; Acquired immune system; Medicine; Biology; Cancer research; Innate immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007442682,0.001048594,0.0006341829,0.00114294,0.0004565049,0.001249547,0.0006518774,0.001207603,0.003065439],"category_scores_gemma":[0.0004934864,0.0008870769,0.0006099344,0.0003455286,0.0009067337,0.0008279542,0.0004715543,0.002491811,0.002017192],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008250476,"about_ca_system_score_gemma":0.0005142812,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003791123,"about_ca_topic_score_gemma":0.0004262414,"domain_scores_codex":[0.9991259,0.0002429883,0.0001097019,0.0001654303,0.0001729766,0.0001831019],"domain_scores_gemma":[0.9987366,0.0001807443,0.000449945,0.000205588,0.00007104371,0.000356149],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009998581,0.0001876005,0.0002841997,0.00007741859,0.00001786777,0.0002316076,0.00004004937,0.0001240392,0.9948258,0.0006403532,0.0001514043,0.002419736],"study_design_scores_gemma":[0.0005407014,0.002269879,0.005767336,0.0001188555,0.00008813048,0.003096311,0.00009795288,0.002127797,0.9705687,0.001037676,0.01426585,0.00002084944],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9670454,0.00943408,0.008369894,0.001169784,0.0002788818,0.0002216225,0.001871898,0.0009551769,0.01065329],"genre_scores_gemma":[0.9770627,0.003483794,0.006209622,0.000464268,0.0001187011,0.0002196681,0.001361679,0.0002309594,0.01084857],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003065439,"threshold_uncertainty_score":0.01025492,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06735948535393264,"score_gpt":0.3825841375680201,"score_spread":0.3152246522140874,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}