{"id":"W2119228816","doi":"10.1073/pnas.1004148107","title":"Architecture of Eph receptor clusters","year":2010,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":269,"is_retracted":false,"has_abstract":true,"ca_institutions":"Structural Genomics Consortium; University of Toronto","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Health and Medical Research Council; Medical Research Council; Ontario Genomics; National Institutes of Health; Knut och Alice Wallenbergs Stiftelse; Karolinska Institutet; Stiftelsen för Strategisk Forskning; National Center for Research Resources; Ontario Genomics Institute; Genome Canada; GlaxoSmithKline; Ontario Innovation Trust; Wellcome Trust; Argonne National Laboratory; U.S. Department of Energy","keywords":"Erythropoietin-producing hepatocellular (Eph) receptor; Ephrin; EPH receptor A2; Ectodomain; Cell biology; Biology; Receptor tyrosine kinase; Signal transduction; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007696751,0.00008000576,0.0001298236,0.0001318218,0.0001539074,0.0000115465,0.00105675,0.00006615236,0.00003973473],"category_scores_gemma":[0.001681816,0.00005096829,0.00008282223,0.0007259151,0.001347033,0.0002646247,0.0001424595,0.0003026784,0.000001952062],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006381628,"about_ca_system_score_gemma":0.0000304485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002035066,"about_ca_topic_score_gemma":4.143665e-8,"domain_scores_codex":[0.9981238,0.000007361065,0.0003013666,0.00024471,0.00117979,0.0001429349],"domain_scores_gemma":[0.9990752,0.0002783785,0.0004839165,0.000008377887,0.0001211125,0.00003295873],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001536659,0.00002208963,0.000784799,0.00002714034,0.000001244004,1.941264e-9,0.0001121724,0.00006647604,0.9712449,0.02700071,0.0002570139,0.0004680625],"study_design_scores_gemma":[0.00008806375,0.0000374203,0.003396071,0.0000420172,0.000003054774,0.000006789298,0.00003269987,0.0002136809,0.9743572,0.02110005,0.000670096,0.00005287854],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897364,0.00001352558,0.000001559352,0.003172896,0.00005370924,0.0001188923,0.0000127815,0.000009227189,0.006880972],"genre_scores_gemma":[0.9979915,0.000009692093,0.001084755,0.0007104315,0.00007773399,0.000003461375,1.521016e-8,0.00000370206,0.0001187009],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00825507,"threshold_uncertainty_score":0.4963201,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04907239050728453,"score_gpt":0.3070869704269809,"score_spread":0.2580145799196964,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}