{"id":"W2119275893","doi":"10.4049/jimmunol.175.12.8051","title":"Human CD4+ T Cells Express TLR5 and Its Ligand Flagellin Enhances the Suppressive Capacity and Expression of FOXP3 in CD4+CD25+ T Regulatory Cells","year":2005,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":368,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity; Vancouver Coastal Health Research Institute; University of British Columbia; Vancouver Coastal Health","funders":"","keywords":"TLR5; Flagellin; IL-2 receptor; FOXP3; Cell biology; Immune system; Biology; Acquired immune system; CD28; Regulatory T cell; T cell; Interleukin 21; Immunology; TLR2; Innate immune system; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000186636,0.0003786236,0.0001916178,0.0002450497,0.0001246442,0.0002872594,0.0001183986,0.000248437,0.002799805],"category_scores_gemma":[0.000149699,0.0001442651,0.0002042896,0.0001455658,0.0001488975,0.0001340282,0.0001653707,0.0004196475,0.0005691452],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002348808,"about_ca_system_score_gemma":0.0001598575,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006107259,"about_ca_topic_score_gemma":0.0009466747,"domain_scores_codex":[0.9997281,0.00006001569,0.00001534143,0.00003344858,0.00005503889,0.0001079484],"domain_scores_gemma":[0.9999183,0.00002069638,0.00001235028,0.00001167085,0.00001137082,0.00002559252],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001475953,0.00003731547,0.000288967,0.00003536308,0.000004447505,0.00003543242,0.00001186091,0.00006209742,0.9971979,0.00005197347,0.00007091139,0.002056214],"study_design_scores_gemma":[0.00009012021,0.001103746,0.00996396,0.00001580065,0.00004260604,0.0005047621,0.00006197807,0.001606712,0.9805744,0.000113732,0.005915633,0.000006534235],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939424,0.001744381,0.001594179,0.0000836925,0.00003438329,0.00002360187,0.000137098,0.00006697264,0.002373122],"genre_scores_gemma":[0.9951071,0.0005454114,0.001167025,0.00007204685,0.00002294513,0.00002064819,0.0004162185,0.000008748189,0.002639857],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002799805,"threshold_uncertainty_score":0.009366274,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01105131971722354,"score_gpt":0.225795079737802,"score_spread":0.2147437600205784,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}