{"id":"W2119286095","doi":"10.1158/1055-9965.epi-03-0448","title":"Increased Rates of Chromosome Breakage in BRCA1 Carriers Are Normalized by Oral Selenium Supplementation","year":2005,"lang":"en","type":"article","venue":"Cancer Epidemiology Biomarkers & Prevention","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"","keywords":"Chromosome; Gene; Genetics; Selenium; Cancer; Andrology; Biology; DNA damage; Internal medicine; Molecular biology; Endocrinology; Medicine; Physiology; Cancer research; DNA; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001476129,0.0002339033,0.0004466855,0.0001100392,0.00004813149,0.000004294493,0.0002000896,0.0003264368,0.0002518458],"category_scores_gemma":[0.0002417448,0.0002465791,0.0001786728,0.0001675404,0.0001486353,0.00002294628,0.00007614682,0.00009937208,0.000005046506],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001420189,"about_ca_system_score_gemma":0.0001203938,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008719625,"about_ca_topic_score_gemma":0.002274625,"domain_scores_codex":[0.997275,0.0009292624,0.0007474171,0.0005350067,0.00009478686,0.0004185355],"domain_scores_gemma":[0.9988889,0.00006775314,0.0005479333,0.0003083322,0.00008151176,0.0001055732],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005015654,0.00009981861,0.1629618,0.0000504934,0.000240693,7.150076e-7,0.00003314692,0.00006520252,0.8148065,0.00003127467,0.01689037,0.004318531],"study_design_scores_gemma":[0.003653822,0.0003274786,0.06085724,0.0001097411,0.00009577395,0.000007173433,0.0001734585,0.0005531829,0.923661,0.0004040221,0.009794506,0.0003626208],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922165,0.004262974,0.001637877,0.0008333426,0.0002238482,0.0005369182,0.0001908693,0.0000220201,0.00007568534],"genre_scores_gemma":[0.9924514,0.0009208578,0.003672652,0.0004584021,0.0001087104,0.0002342538,0.001778116,0.00002885789,0.0003466929],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1088545,"threshold_uncertainty_score":0.9999986,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02139977618596476,"score_gpt":0.3390849318627507,"score_spread":0.317685155676786,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}