{"id":"W2119311022","doi":"10.1002/dvdy.24342","title":"MicroRNA dysregulation in response to RARĪ²2 inhibition reveals a negative feedback loop between MicroRNAs 1, 133a, and RARĪ²2 during tail and spinal cord regeneration in the adult newt","year":2015,"lang":"en","type":"article","venue":"Developmental Dynamics","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; University of Pittsburgh","keywords":"Biology; microRNA; Cell biology; Regeneration (biology); Zebrafish; Neuroscience; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006538361,0.0002026654,0.0001705152,0.0001581891,0.0001123898,0.00004562678,0.00008512977,0.0002056729,0.000001086046],"category_scores_gemma":[0.0001342813,0.0001894197,0.00001892267,0.0002657654,0.00009702292,0.00002900727,0.0001362063,0.0001123596,0.000005412488],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002167921,"about_ca_system_score_gemma":0.0001086812,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004949833,"about_ca_topic_score_gemma":0.001238465,"domain_scores_codex":[0.9985929,0.0002553727,0.000372947,0.0004141227,0.0001277085,0.0002370133],"domain_scores_gemma":[0.9995999,0.00002361929,0.0001038369,0.0001105484,0.000074054,0.00008797863],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.004423584,0.00004302288,0.245798,0.00002745648,0.00002483433,0.00001311145,0.00133367,0.00004150563,0.735644,0.00005534539,0.0001655477,0.01242998],"study_design_scores_gemma":[0.001687894,0.0003059231,0.916706,0.00008091721,0.000006153453,0.00008861792,0.001152447,0.00009964465,0.07917553,0.000313238,0.0001132785,0.0002703262],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978121,0.0001136143,0.0002893012,0.001105528,0.0000563928,0.000522115,0.00002743576,0.000007365169,0.00006617845],"genre_scores_gemma":[0.9941449,0.00004141503,0.004434473,0.0003221296,0.0000475121,0.0000411829,0.0006699927,0.00001477182,0.0002835999],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.670908,"threshold_uncertainty_score":0.772431,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01250812741425398,"score_gpt":0.2494801406844772,"score_spread":0.2369720132702232,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}