{"id":"W2119319172","doi":"10.1126/science.1090148","title":"Control of Effector CD8 <sup>+</sup> T Cell Function by the Transcription Factor <i>Eomesodermin</i>","year":2003,"lang":"en","type":"article","venue":"Science","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":993,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences","keywords":"Effector; Cell biology; CD8; Biology; Granzyme; Cytotoxic T cell; Granzyme B; Perforin; Transcription factor; Ectopic expression; Immune system; Immunology; In vitro; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004843339,0.0001213042,0.0001431225,0.00008399113,0.0003461758,0.00002379444,0.0002020458,0.00009321105,0.001379121],"category_scores_gemma":[0.00009768584,0.00008239457,0.00008639332,0.0003021762,0.000489071,0.0002929708,0.000008355933,0.0002153637,0.0005065741],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004640348,"about_ca_system_score_gemma":0.00007346785,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003500755,"about_ca_topic_score_gemma":0.000001205259,"domain_scores_codex":[0.9989548,0.0002163333,0.0002231291,0.0002525084,0.0000818855,0.0002712935],"domain_scores_gemma":[0.9993905,0.0001173609,0.0001111258,0.0002469332,0.0001153731,0.00001867825],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009674066,0.0000716517,0.0003295241,0.000007372636,0.00001111013,6.627062e-8,0.0002599514,0.00003261667,0.9931414,0.00016155,0.004703218,0.001184786],"study_design_scores_gemma":[0.0009654883,0.0002586475,0.0008817549,0.000006916539,0.00002340291,0.0000128874,0.0002937008,0.00009716846,0.7655513,0.00001561099,0.2318057,0.00008747689],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9712111,0.002411536,0.01513573,0.0001895785,0.004929886,0.0004757599,0.00002233015,0.00006556202,0.005558536],"genre_scores_gemma":[0.9920409,0.00002091061,0.000005821294,0.0004047352,0.00001052434,0.0000158147,0.0000125733,0.000006601297,0.007482166],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2275902,"threshold_uncertainty_score":0.9995338,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006934073618230583,"score_gpt":0.203950137397852,"score_spread":0.1970160637796214,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}