{"id":"W2119319172","doi":"10.1126/science.1090148","title":"Control of Effector CD8 <sup>+</sup> T Cell Function by the Transcription Factor <i>Eomesodermin</i>","year":2003,"lang":"en","type":"article","venue":"Science","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":993,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences","keywords":"Effector; Cell biology; CD8; Biology; Granzyme; Cytotoxic T cell; Granzyme B; Perforin; Transcription factor; Ectopic expression; Immune system; Immunology; In vitro; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001124032,0.0002380212,0.0001129124,0.0001216654,0.00009602885,0.0003947773,0.00008880485,0.0001358187,0.001069004],"category_scores_gemma":[0.000163234,0.00008088938,0.00009229317,0.00007050313,0.0002527314,0.0002089889,0.0001675968,0.0004100527,0.0004960641],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001762023,"about_ca_system_score_gemma":0.0001021158,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000079705,"about_ca_topic_score_gemma":0.0001380642,"domain_scores_codex":[0.9999124,0.00002101799,0.00000754357,0.00001395586,0.00001902826,0.00002607668],"domain_scores_gemma":[0.9999114,0.00002107706,0.00002590832,0.00001009558,0.00001097496,0.0000206103],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005455393,0.000005897682,0.0001687376,0.00001159341,5.207647e-7,0.00003812308,0.000007375682,0.00004696783,0.997411,0.0001853821,0.00002881339,0.002041029],"study_design_scores_gemma":[0.00002065791,0.0001780033,0.003851916,0.000005799107,0.000004969401,0.0003428902,0.00004526558,0.001549632,0.9900162,0.0003187245,0.003663248,0.000002782219],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912826,0.001427755,0.003500927,0.00009748116,0.00002787879,0.00001292237,0.0001188382,0.00008582763,0.00344571],"genre_scores_gemma":[0.9948861,0.0005143257,0.002006143,0.00002915009,0.0000162289,0.00001142911,0.0001324231,0.00002101425,0.0023831],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001069004,"threshold_uncertainty_score":0.003576219,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006934073618230583,"score_gpt":0.203950137397852,"score_spread":0.1970160637796214,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}