{"id":"W2119358116","doi":"10.4049/jimmunol.0903292","title":"The Src-Like Adaptor Protein Regulates GM-CSFR Signaling and Monocytic Dendritic Cell Maturation","year":2011,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; Ontario Institute for Cancer Research; University of Toronto","funders":"Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Signal transducing adaptor protein; CD86; CD11c; Cell biology; CD80; MHC class II; Bone marrow; Dendritic cell; Protein kinase B; Biology; Phosphorylation; T cell; Immunology; Immune system; CD40; Phenotype; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001263995,0.0002130062,0.0003272234,0.0001193324,0.0007021967,0.0000311626,0.0005842132,0.000235433,0.0001215965],"category_scores_gemma":[0.0001261878,0.0001153133,0.0001170841,0.0001119273,0.0007803199,0.0001952095,0.00009771557,0.000702627,0.00006290899],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004647715,"about_ca_system_score_gemma":0.0001187562,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007664658,"about_ca_topic_score_gemma":0.00000609523,"domain_scores_codex":[0.9975303,0.001246462,0.0006544689,0.0001162267,0.00005103796,0.0004014522],"domain_scores_gemma":[0.9981618,0.0006823244,0.0005949701,0.0003672111,0.0001795214,0.0000141796],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005432277,0.0000661405,0.00002144686,0.000009890306,0.0004029471,0.000006803179,0.002462409,0.000001828995,0.9869848,0.0004159148,0.0001831235,0.004012395],"study_design_scores_gemma":[0.001826183,0.001344471,0.004786531,0.0001098985,0.0001461776,0.002073005,0.003358134,0.000004459631,0.9769578,0.001408746,0.007798708,0.0001858675],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8859915,0.1122303,0.0001571683,0.0003816427,0.0008328523,0.0002446414,0.000001571942,0.00001811449,0.000142196],"genre_scores_gemma":[0.9937904,0.003245317,0.00015044,0.00009877648,0.00003655574,0.000008432669,0.000001573798,0.00002366897,0.002644851],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.108985,"threshold_uncertainty_score":0.5400801,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01515057681120822,"score_gpt":0.2074256441522744,"score_spread":0.1922750673410662,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}