{"id":"W2119358116","doi":"10.4049/jimmunol.0903292","title":"The Src-Like Adaptor Protein Regulates GM-CSFR Signaling and Monocytic Dendritic Cell Maturation","year":2011,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; Ontario Institute for Cancer Research; University of Toronto","funders":"Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Signal transducing adaptor protein; CD86; CD11c; Cell biology; CD80; MHC class II; Bone marrow; Dendritic cell; Protein kinase B; Biology; Phosphorylation; T cell; Immunology; Immune system; CD40; Phenotype; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009528362,0.0002744047,0.0001720976,0.0001268906,0.0001763578,0.0002908397,0.0001373495,0.0002543362,0.000962648],"category_scores_gemma":[0.00007390084,0.0001275142,0.0002228024,0.0001260781,0.0001538398,0.0002354831,0.0002968459,0.0004632498,0.0007281361],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002658447,"about_ca_system_score_gemma":0.0002136986,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000309551,"about_ca_topic_score_gemma":0.0004846467,"domain_scores_codex":[0.9998523,0.00002172199,0.00001127367,0.0000294349,0.00003695641,0.00004825378],"domain_scores_gemma":[0.9999449,0.000003219385,0.00001895586,0.000004369741,0.000009059488,0.00001946579],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00011459,0.000009534389,0.0001959083,0.00003301919,0.000001833673,0.0001031001,0.00001019103,0.00003421832,0.9983103,0.0001072444,0.00006801744,0.001012118],"study_design_scores_gemma":[0.00006815348,0.0002542338,0.02406557,0.00001934244,0.00002078229,0.001215517,0.00009559569,0.002471202,0.9628927,0.0002018657,0.008684326,0.00001079102],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886963,0.004880313,0.002716499,0.0002186603,0.000050798,0.00003219225,0.0004934409,0.0001060862,0.002805571],"genre_scores_gemma":[0.9938794,0.001715545,0.001353348,0.00005090977,0.00001998614,0.00002324581,0.0004328523,0.00001533965,0.002509255],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000962648,"threshold_uncertainty_score":0.003220379,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01515057681120822,"score_gpt":0.2074256441522744,"score_spread":0.1922750673410662,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}