{"id":"W2119361192","doi":"10.4049/jimmunol.1100885","title":"B Cell-Derived IL-15 Enhances CD8 T Cell Cytotoxicity and Is Increased in Multiple Sclerosis Patients","year":2011,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Notre-Dame; Centre Hospitalier de l’Université de Montréal","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Cytotoxic T cell; CD8; Immunology; Cytokine; Interleukin 21; T cell; CD40; Biology; Chemistry; Immune system; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004240601,0.0001682663,0.0003222354,0.0001971373,0.0001708858,0.000007727487,0.0002785316,0.0002208694,0.001136108],"category_scores_gemma":[0.00009690838,0.0001166757,0.00008572156,0.0001082895,0.0002850258,0.0002072792,0.00009364854,0.0006236284,0.0001778167],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004961076,"about_ca_system_score_gemma":0.0000380272,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005699074,"about_ca_topic_score_gemma":0.00002636283,"domain_scores_codex":[0.9984356,0.0005765745,0.0005598144,0.0001250623,0.0000375496,0.0002654298],"domain_scores_gemma":[0.9988207,0.0002368702,0.0005584126,0.0001960836,0.0001708892,0.00001699392],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002052626,0.000429668,0.009814422,0.000006640849,0.00008982822,0.000001283206,0.003460633,4.926549e-7,0.9820726,0.000002660393,0.001615199,0.0004539405],"study_design_scores_gemma":[0.003096957,0.0008670972,0.1517725,0.00003246588,0.00004295063,0.00004767135,0.00138308,0.00000245007,0.8415304,0.00002339282,0.001094351,0.0001067107],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941597,0.003375691,0.00006294114,0.00006359598,0.001331732,0.0001391221,0.000004318547,0.00001053424,0.0008523935],"genre_scores_gemma":[0.997202,0.001902758,0.00004989615,0.0003147269,0.00001474867,0.000003440105,0.000006372568,0.00001241303,0.0004936385],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1419581,"threshold_uncertainty_score":0.999777,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02317755656110067,"score_gpt":0.1986766152321884,"score_spread":0.1754990586710877,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}