{"id":"W2119361192","doi":"10.4049/jimmunol.1100885","title":"B Cell-Derived IL-15 Enhances CD8 T Cell Cytotoxicity and Is Increased in Multiple Sclerosis Patients","year":2011,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Notre-Dame; Centre Hospitalier de l’Université de Montréal","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Cytotoxic T cell; CD8; Immunology; Cytokine; Interleukin 21; T cell; CD40; Biology; Chemistry; Immune system; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001711588,0.0003980142,0.0004667522,0.001056083,0.0002478229,0.0004072317,0.0001226418,0.0005245496,0.002907987],"category_scores_gemma":[0.0005235855,0.0001879156,0.0001802432,0.0003429851,0.0001556358,0.0001763231,0.0002703518,0.0004751474,0.0007988491],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001840989,"about_ca_system_score_gemma":0.0000945558,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004152432,"about_ca_topic_score_gemma":0.0003397473,"domain_scores_codex":[0.9997887,0.00004748426,0.00003546342,0.00004585877,0.00004941092,0.00003295127],"domain_scores_gemma":[0.9995744,0.00006050029,0.0001577529,0.00003043744,0.00006036347,0.0001165273],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00524488,0.0004555117,0.2499287,0.0002414413,0.000171404,0.00286133,0.0005099071,0.000154647,0.7096202,0.0001151397,0.0006709005,0.03002593],"study_design_scores_gemma":[0.0001663582,0.001663215,0.9386707,0.00005255882,0.0001453409,0.0107049,0.0001899176,0.0004648498,0.04360939,0.0002021078,0.004110626,0.00002013463],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976502,0.0009544874,0.0001609164,0.00004127074,0.000008836863,0.00001072964,0.0001589728,0.00005480677,0.0009597972],"genre_scores_gemma":[0.9984124,0.0002726607,0.000245181,0.00007027354,0.00001838309,0.00001634676,0.0002518467,0.000009805134,0.000703209],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002907987,"threshold_uncertainty_score":0.009728193,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02317755656110067,"score_gpt":0.1986766152321884,"score_spread":0.1754990586710877,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}