{"id":"W2119504522","doi":"10.1095/biolreprod.111.090910","title":"Mouse Embryos Stressed by Physiological Levels of Osmolarity Become Arrested in the Late 2-Cell Stage Before Entry into M Phase1","year":2011,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Ottawa Hospital","funders":"","keywords":"Biology; Osmotic concentration; Osmolyte; Cell biology; Embryo; Blastocyst; Embryogenesis; Osmotic shock; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010843,0.0001683494,0.0004621697,0.00008164508,0.00005158035,0.000001149802,0.000187247,0.0003127773,0.0001099698],"category_scores_gemma":[0.0005635725,0.0001055925,0.000101933,0.0001997013,0.0007857939,0.00006597659,0.00005210815,0.0003585147,0.00000460335],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002836612,"about_ca_system_score_gemma":0.00004240558,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000395086,"about_ca_topic_score_gemma":0.00001955011,"domain_scores_codex":[0.9980952,0.0004773036,0.0004881321,0.0006409495,0.00008672926,0.0002117429],"domain_scores_gemma":[0.9985467,0.00003963189,0.000304481,0.000920301,0.0001526826,0.00003626896],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00214833,0.00142392,0.2319706,0.00012969,0.00005243991,0.000002157961,0.0009852998,7.368325e-7,0.7604993,0.00006573519,0.0001276419,0.002594197],"study_design_scores_gemma":[0.000665839,0.0009428818,0.5691052,0.000009333797,0.00002255736,0.000003970974,0.0002536573,0.000002332655,0.4280488,0.0006256918,0.0002581366,0.00006154858],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971114,0.001358326,0.00007147329,0.0003663047,0.0002339277,0.0005741835,0.00006341938,0.00003030136,0.0001905998],"genre_scores_gemma":[0.9985279,0.0000863902,0.0002862016,0.00004211216,0.00009711267,0.00002097702,0.0001198087,0.000007254524,0.0008122275],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3371346,"threshold_uncertainty_score":0.4305937,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05643533344147268,"score_gpt":0.3019006820033716,"score_spread":0.2454653485618989,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}