{"id":"W2119588819","doi":"10.1101/gad.234534.113","title":"Impacts of the ubiquitous factor Zelda on Bicoid-dependent DNA binding and transcription in <i>Drosophila</i>","year":2014,"lang":"en","type":"article","venue":"Genes & Development","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":117,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Research Resources; National Institute of General Medical Sciences; National Institutes of Health; York University","keywords":"Biology; Enhancer; Drosophila embryogenesis; Transcription factor; Genetics; DNA binding site; DNA-binding protein; Binding site; Cell biology; Gene; Transcription (linguistics); DNA; Mutant; Drosophila melanogaster; Gene expression; Promoter","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001290155,0.000378265,0.0002219188,0.0003173641,0.0002295667,0.0004294825,0.0003644268,0.0002862238,0.00120136],"category_scores_gemma":[0.0001771502,0.0003136744,0.0002655635,0.0001529238,0.0003666009,0.0001286132,0.0005172439,0.0004716857,0.0005205396],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008935112,"about_ca_system_score_gemma":0.0003392405,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003971181,"about_ca_topic_score_gemma":0.006361912,"domain_scores_codex":[0.9997106,0.00004368944,0.00002926013,0.00007196786,0.00007982131,0.00006450622],"domain_scores_gemma":[0.9997959,0.00005060985,0.00005993184,0.00001906524,0.00001376134,0.00006085073],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007957711,0.000009397741,0.0002081274,0.00001161278,0.000002485484,0.00001607199,0.00000552007,0.00004113229,0.9992294,0.00003141002,0.000008867953,0.0003563458],"study_design_scores_gemma":[0.00001832533,0.00009192609,0.01209356,0.00000595109,0.00001127065,0.0001173762,0.0000308834,0.001079345,0.9853141,0.00003090022,0.001197431,0.000008879656],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964465,0.0007741073,0.001251794,0.00005173599,0.00001184602,0.00001118643,0.0004293732,0.00007705934,0.0009464073],"genre_scores_gemma":[0.9963925,0.0002365616,0.001096433,0.00005763064,0.000002274303,0.00001419745,0.0006359338,0.00006157616,0.001502809],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003971181,"threshold_uncertainty_score":0.007896125,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007597627147747955,"score_gpt":0.2059626446857783,"score_spread":0.1983650175380303,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}