{"id":"W2119672797","doi":"10.1210/en.2007-1136","title":"Roles of Rho Guanosine 5′-Triphosphatase A, Rho Kinases, and Extracellular Signal Regulated Kinase (1/2) in Prostaglandin E2-Mediated Migration of First-Trimester Human Extravillous Trophoblast","year":2007,"lang":"en","type":"article","venue":"Endocrinology","topic":"Pregnancy and preeclampsia studies","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"RHOA; Trophoblast; Cell biology; Kinase; MAPK/ERK pathway; Biology; Prostaglandin E2 receptor; Rho-associated protein kinase; Cell migration; Signal transduction; Endocrinology; Internal medicine; Placenta; Receptor; Agonist; Cell; Medicine; Biochemistry; Fetus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002084989,0.0003556996,0.0002272768,0.0002648591,0.0001661931,0.0003255137,0.0001138488,0.0002831298,0.0005244306],"category_scores_gemma":[0.0001247617,0.0001732029,0.000375201,0.00008988302,0.0002125316,0.0002179834,0.0001726043,0.0003951007,0.0001948219],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001641454,"about_ca_system_score_gemma":0.0002849317,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004114314,"about_ca_topic_score_gemma":0.0007094347,"domain_scores_codex":[0.9998883,0.00003269943,0.0000118366,0.00001576916,0.00001843175,0.00003296071],"domain_scores_gemma":[0.9999313,0.00001385729,0.00002149778,0.000008546745,0.000006071611,0.00001874026],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003488843,0.00003834839,0.001053654,0.00007690761,0.000007724164,0.0003845507,0.00005573924,0.00007407377,0.9947889,0.0003035484,0.00003704262,0.002830718],"study_design_scores_gemma":[0.0001150578,0.0008596209,0.06861919,0.00002728915,0.00007899903,0.002493265,0.0001715144,0.002035165,0.9199899,0.0004667244,0.005124276,0.00001903546],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9842162,0.01057905,0.00240617,0.0002390674,0.00003795554,0.00005103908,0.0002099422,0.00005841645,0.002202244],"genre_scores_gemma":[0.9903325,0.005067115,0.002267546,0.00005816447,0.00002446009,0.00007774453,0.0003098978,0.000008777419,0.001853673],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005244306,"threshold_uncertainty_score":0.001754403,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01326941786665841,"score_gpt":0.2572561125484638,"score_spread":0.2439866946818053,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}