{"id":"W2119803090","doi":"10.1111/papr.12329","title":"Pooled Post Hoc Analysis of Population Pharmacokinetics of Oxycodone and Acetaminophen Following Multiple Oral Doses of Biphasic Immediate‐Release/Extended‐Release Oxycodone/Acetaminophen Tablets","year":2015,"lang":"en","type":"article","venue":"Pain Practice","topic":"Pain Management and Opioid Use","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Mallinckrodt Pharmaceuticals","keywords":"Oxycodone; Medicine; Acetaminophen; Pharmacokinetics; Post-hoc analysis; Anesthesia; Immediate release; Post hoc; Pharmacology; Population; Opioid; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004194254,0.0006274161,0.001558454,0.0003686982,0.0001449989,0.000678568,0.0004283677,0.0004567848,0.002508589],"category_scores_gemma":[0.007542182,0.0002578699,0.001366808,0.0002671543,0.0003141144,0.0004900409,0.0003406741,0.0006593189,0.0002451387],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004435054,"about_ca_system_score_gemma":0.0006377265,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004728436,"about_ca_topic_score_gemma":0.0004800544,"domain_scores_codex":[0.9974704,0.001040537,0.00020027,0.0006237685,0.0005219511,0.0001430878],"domain_scores_gemma":[0.9955078,0.002012859,0.001140593,0.0005564202,0.0005972898,0.0001850744],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.5700485,0.008780285,0.08816447,0.001496814,0.01252418,0.0003786292,0.0005314274,0.005568895,0.1046649,0.0002512307,0.001837292,0.2057534],"study_design_scores_gemma":[0.01530409,0.4118662,0.4902366,0.00008277866,0.01211754,0.0004685064,0.0002798542,0.01579196,0.04992076,0.000297518,0.003510941,0.0001231653],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944329,0.0006947952,0.00283342,0.00002882313,0.00006208803,0.0007209461,0.0007007436,0.00006102427,0.0004653428],"genre_scores_gemma":[0.9944109,0.0002200821,0.002701644,0.00007769594,0.00006608719,0.0009580284,0.0008347319,0.00002072643,0.0007100507],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004194254,"threshold_uncertainty_score":0.02218163,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0234971356771035,"score_gpt":0.3036026624913057,"score_spread":0.2801055268142023,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}