{"id":"W2119818163","doi":"10.1001/jama.295.2.165","title":"Comparison of β-Blockers, Amiodarone Plus β-Blockers, or Sotalol for Prevention of Shocks From Implantable Cardioverter Defibrillators<SUBTITLE>The OPTIC Study: A Randomized Trial</SUBTITLE>","year":2006,"lang":"en","type":"article","venue":"JAMA","topic":"Cardiac pacing and defibrillation studies","field":"Medicine","cited_by":781,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Sotalol; Medicine; Amiodarone; Beta blocker; Cardiology; Internal medicine; Antiarrhythmic agent; Randomized controlled trial; Anesthesia; Implantable cardioverter-defibrillator; Hazard ratio; Shock (circulatory); Atrial fibrillation; Confidence interval; Heart failure; Heart disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009935875,0.0003608502,0.003197015,0.000185569,0.0001826596,0.00004816111,0.00007347223,0.0002044236,0.00003598842],"category_scores_gemma":[0.0005204117,0.0002427984,0.0009721423,0.0003318339,0.0002043398,0.00009507862,0.0000996692,0.0001487773,0.00002167882],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001486381,"about_ca_system_score_gemma":0.000191299,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009529191,"about_ca_topic_score_gemma":0.0002087163,"domain_scores_codex":[0.9967265,0.0003048742,0.001357068,0.0004673487,0.0007639689,0.0003802887],"domain_scores_gemma":[0.9967446,0.001433442,0.0006995032,0.0006603251,0.0003754499,0.00008671144],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6336291,0.0006276811,0.00817157,0.0003140156,0.004869858,0.000005361623,0.002375813,0.0003295365,0.005023754,0.0002318522,0.3420335,0.00238803],"study_design_scores_gemma":[0.9168523,0.0018239,0.004943498,0.0004705042,0.005822378,0.0001126353,0.002369925,0.001566799,0.008704162,0.0003532171,0.05642751,0.0005531655],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9719836,0.004029607,0.001030053,0.0001546463,0.0006855503,0.00503236,0.0003261458,0.00008944083,0.01666862],"genre_scores_gemma":[0.995009,0.00007579625,0.001278809,0.0000267123,0.0008614895,0.000194321,0.0001744013,0.00005310138,0.002326368],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.285606,"threshold_uncertainty_score":0.9901032,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03139353282727531,"score_gpt":0.3253611856177263,"score_spread":0.293967652790451,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}