{"id":"W2119985621","doi":"10.1093/hmg/ddu596","title":"ATRX promotes gene expression by facilitating transcriptional elongation through guanine-rich coding regions","year":2014,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":104,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children’s Health Research Institute; Western University","funders":"Canadian Institutes of Health Research","keywords":"ATRX; Biology; Histone; Death-associated protein 6; Gene; Genetics; Epigenetics; Chromatin; DNA methylation; Gene expression; Transcription factor; Mutation; Nuclear protein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008900518,0.0002090993,0.000116807,0.0001654149,0.0001119328,0.0001602587,0.0001737337,0.0001503601,0.001544819],"category_scores_gemma":[0.0001006323,0.0001250961,0.0001661218,0.0000820779,0.0001887926,0.0001191444,0.0002441269,0.000230266,0.0004914817],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001891277,"about_ca_system_score_gemma":0.0001143184,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004497266,"about_ca_topic_score_gemma":0.0008176839,"domain_scores_codex":[0.9999257,0.00001417273,0.000004143497,0.00002590612,0.00001874288,0.00001135448],"domain_scores_gemma":[0.9999151,0.00001580765,0.00003130327,0.00001066067,0.000007274713,0.00001978636],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001812301,0.000003093948,0.0002596652,0.00001109154,0.000002001619,0.00002170113,0.000005179422,0.00003617201,0.9990958,0.00006151845,0.000007659963,0.000478013],"study_design_scores_gemma":[0.00001333406,0.0001350126,0.02085137,0.000008504468,0.000008448351,0.0002631448,0.00002264545,0.001022016,0.9757032,0.0001561595,0.001813417,0.000002739996],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925897,0.0007670814,0.004775668,0.00005889912,0.000007091833,0.000006649535,0.0001340904,0.0001301853,0.00153055],"genre_scores_gemma":[0.9949097,0.0003180712,0.002786469,0.00002259983,0.000004093938,0.000007849884,0.0002089665,0.0000219503,0.001720179],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001544819,"threshold_uncertainty_score":0.005167961,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01281085923472265,"score_gpt":0.2443883643505105,"score_spread":0.2315775051157878,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}