{"id":"W2119985621","doi":"10.1093/hmg/ddu596","title":"ATRX promotes gene expression by facilitating transcriptional elongation through guanine-rich coding regions","year":2014,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":104,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children’s Health Research Institute; Western University","funders":"Canadian Institutes of Health Research","keywords":"ATRX; Biology; Histone; Death-associated protein 6; Gene; Genetics; Epigenetics; Chromatin; DNA methylation; Gene expression; Transcription factor; Mutation; Nuclear protein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000185295,0.0002701907,0.0001814606,0.0000351768,0.0003147507,0.00006662889,0.0002823398,0.0002142239,0.00002042494],"category_scores_gemma":[0.00005454698,0.000297235,0.000126703,0.00008105613,0.00009464536,0.000006084444,0.0001005047,0.0001310678,0.000008979513],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002510183,"about_ca_system_score_gemma":0.00003413853,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007647278,"about_ca_topic_score_gemma":0.0000102016,"domain_scores_codex":[0.9983665,0.0001292545,0.000373824,0.000533244,0.0002552554,0.0003418713],"domain_scores_gemma":[0.9991189,0.0000132234,0.00015137,0.0004945114,0.0001305172,0.00009153005],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000007076698,0.00005684302,0.0003067079,0.00002850508,0.00003049867,0.000001428915,0.0002264698,0.001114357,0.9956997,0.001477164,0.000774325,0.0002769471],"study_design_scores_gemma":[0.0007399209,0.0003604255,0.001121371,0.00003112973,0.0000422853,0.00001901847,0.0001231538,0.00284686,0.9848468,0.003482088,0.005899767,0.0004871312],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.766691,0.0007833977,0.2315528,0.00006907724,0.00007259315,0.0002043523,0.00004185578,0.00002390568,0.0005610455],"genre_scores_gemma":[0.9615394,0.0001142061,0.03630115,0.000233778,0.000140964,0.0000339982,0.001333958,0.00005942561,0.0002431579],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1952516,"threshold_uncertainty_score":0.999948,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01281085923472265,"score_gpt":0.2443883643505105,"score_spread":0.2315775051157878,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}