{"id":"W2120001362","doi":"10.1371/journal.pgen.1005659","title":"Genetic Interactions Implicating Postreplicative Repair in Okazaki Fragment Processing","year":2015,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institutes of Health; National Institute of General Medical Sciences; Canadian Institute for Advanced Research; National Human Genome Research Institute; University of Minnesota; Leukemia and Lymphoma Society","keywords":"Okazaki fragments; Proliferating cell nuclear antigen; Biology; DNA replication; DNA mismatch repair; Ubiquitin; Replication factor C; DNA repair; Cell biology; Postreplication repair; DNA polymerase delta; Molecular biology; Genetics; DNA; Eukaryotic DNA replication; Reverse transcriptase; Polymerase chain reaction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001432204,0.00020174,0.0001625916,0.00007426143,0.00005505719,0.00002331234,0.0002530889,0.0001156453,0.00001014051],"category_scores_gemma":[0.0001400517,0.0002153436,0.00007703545,0.0001766127,0.00004952715,0.000004965804,0.0002416564,0.0001423813,0.00003431613],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008072825,"about_ca_system_score_gemma":0.0001792199,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009255123,"about_ca_topic_score_gemma":0.00006347435,"domain_scores_codex":[0.9984624,0.00007367586,0.0003610833,0.0005623012,0.0002058837,0.0003346919],"domain_scores_gemma":[0.9988278,0.00001067276,0.0001431183,0.0006440327,0.0001984415,0.0001759918],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004703863,0.0003335369,0.0149463,0.00003667048,0.00005604813,0.00000932548,0.0005536482,0.0006218724,0.9741258,0.00002633216,0.001077198,0.008166237],"study_design_scores_gemma":[0.0006273675,0.0004354042,0.002903612,0.00006189036,0.00004193847,0.00005374462,0.0006716867,0.01503348,0.9692197,0.0004503235,0.01008899,0.0004118017],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951921,0.001348055,0.001151955,0.0001548903,0.00008574108,0.0004097701,0.00001800724,0.00007611969,0.001563322],"genre_scores_gemma":[0.9725254,0.00004758998,0.02643179,0.0003070369,0.0001931044,0.0001602916,0.00003686768,0.00005055156,0.0002473916],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02527984,"threshold_uncertainty_score":0.8781458,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02885162072172514,"score_gpt":0.2911870080656241,"score_spread":0.2623353873438989,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}