{"id":"W2120004345","doi":"10.1093/molbev/msp134","title":"Interrogating 11 Fast-Evolving Genes for Signatures of Recent Positive Selection in Worldwide Human Populations","year":2009,"lang":"en","type":"article","venue":"Molecular Biology and Evolution","topic":"Genetic Mapping and Diversity in Plants and Animals","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Biology; Genetics; Single-nucleotide polymorphism; Evolutionary biology; Gene; Lineage (genetic); Natural selection; Selection (genetic algorithm); Population; Negative selection; Candidate gene; Haplotype; Allele frequency; SNP genotyping; Balancing selection; Allele; Genome; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003770233,0.0001599456,0.0002560645,0.0008190302,0.0002228122,0.0003311144,0.0001852415,0.0002590029,0.0009371195],"category_scores_gemma":[0.001024959,0.000101951,0.000236887,0.0009439462,0.0003342486,0.0001648113,0.0002767617,0.0002879853,0.0001052626],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001015381,"about_ca_system_score_gemma":0.0001162814,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001264108,"about_ca_topic_score_gemma":0.002292613,"domain_scores_codex":[0.9997979,0.00004155727,0.00001545623,0.00008831813,0.00002930647,0.00002739009],"domain_scores_gemma":[0.9994753,0.0002878874,0.0001179736,0.00004062828,0.00003513286,0.00004305409],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004939746,0.00004495047,0.7868429,0.0001267757,0.0003731201,0.0008975727,0.0009074033,0.001041816,0.1762927,0.0003159209,0.0001227862,0.03254008],"study_design_scores_gemma":[0.00001805523,0.00008685044,0.9931251,0.00001547282,0.0001194321,0.001039858,0.0002992726,0.0007286633,0.003811985,0.0002609819,0.0004845055,0.000009817647],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992639,0.0001867488,0.0002980225,0.00001536268,0.00000121782,0.000002180884,0.0000933465,0.000003465836,0.000135851],"genre_scores_gemma":[0.9986737,0.0001338445,0.0007794203,0.00002134319,0.000005746601,0.000005600178,0.0002687579,0.000005041033,0.0001066816],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001264108,"threshold_uncertainty_score":0.003135026,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01499878695932684,"score_gpt":0.2897617082765417,"score_spread":0.2747629213172149,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}