{"id":"W2120013965","doi":"10.1007/s002810000014","title":"The role of CpG in DNA vaccines","year":2000,"lang":"en","type":"review","venue":"Springer Seminars in Immunopathology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":45,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa; Ottawa Hospital","funders":"","keywords":"Immune system; DNA vaccination; Immunology; Biology; Antigen; CpG site; Virology; Immunotherapy; Antibody; Cytotoxic T cell; DNA methylation; Immunization; Gene; In vitro; Gene expression; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00155682,0.0007173581,0.002608158,0.0008827242,0.0001829628,0.00002067007,0.001543394,0.001321273,0.0007976055],"category_scores_gemma":[0.0002380396,0.0005259826,0.0005551078,0.0007539366,0.0006442121,0.00008815845,0.0003143558,0.001598369,0.0004135746],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001585792,"about_ca_system_score_gemma":0.0003380408,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001113442,"about_ca_topic_score_gemma":0.00004381846,"domain_scores_codex":[0.9943255,0.002030538,0.001948401,0.000638046,0.00005991698,0.0009976301],"domain_scores_gemma":[0.9963802,0.001525487,0.0006798466,0.00136156,0.00004047209,0.00001244094],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004925115,0.0001966449,0.0001698062,0.0004779308,0.0001532095,0.00005560563,0.0004541582,3.752321e-7,0.002471146,0.0002817425,0.0001170838,0.9951298],"study_design_scores_gemma":[0.0007498392,0.0002291005,0.0003781156,0.006925567,0.0001140931,0.0007330276,0.0002136273,1.466479e-7,0.001567197,0.0002723529,0.9883582,0.000458705],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004933279,0.9900445,4.591947e-7,0.00001815624,0.001252548,0.0007891422,0.00002645718,0.00003898245,0.002896512],"genre_scores_gemma":[0.001024785,0.9928851,0.0000174653,0.00001440732,0.00002572551,0.0004531228,0.00004636441,0.00009419987,0.005438878],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9946711,"threshold_uncertainty_score":0.9999752,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01058825403634891,"score_gpt":0.2699680382931814,"score_spread":0.2593797842568326,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}