{"id":"W2120063383","doi":"10.1093/nar/28.9.e41","title":"Retro-recombination screening of a mouse embryonic stem cell genomic library","year":2000,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Cancer Foundation; University of Calgary","funders":"","keywords":"Biology; Plasmid; Bacteriophage; Genetics; Genomic library; Recombination; FLP-FRT recombination; Homologous recombination; Cre-Lox recombination; Lambda phage; Genome; Gene; clone (Java method); Computational biology; Genetic recombination; Transgene; Escherichia coli; Base sequence; Genetically modified mouse","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007155948,0.000721926,0.0007219514,0.00150427,0.0002904767,0.0003956864,0.0005798617,0.0004226412,0.002379491],"category_scores_gemma":[0.0002431225,0.0003064037,0.0006614166,0.0008531245,0.0003199836,0.0001750851,0.0003500005,0.000865658,0.001356594],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003080131,"about_ca_system_score_gemma":0.0003844112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005465931,"about_ca_topic_score_gemma":0.001252689,"domain_scores_codex":[0.9995103,0.00008899641,0.00005021512,0.0001108613,0.0001770666,0.0000625959],"domain_scores_gemma":[0.9997002,0.0001130525,0.00004959992,0.00004640337,0.00004029649,0.00005051701],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002293835,0.000018048,0.0000655804,0.00003396107,0.000004842728,0.00005592222,0.00001517032,0.00002545406,0.9980307,0.0000760915,0.00003047731,0.001620652],"study_design_scores_gemma":[0.0000146932,0.0002699411,0.002606522,0.000009227069,0.00004967257,0.0002844235,0.00001618186,0.0006341917,0.9922146,0.0000623354,0.003831333,0.000006933088],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7265408,0.002992499,0.2499113,0.0003428618,0.0001467664,0.001839451,0.007156929,0.003120331,0.00794913],"genre_scores_gemma":[0.70012,0.006006772,0.2287505,0.0003928675,0.00006457334,0.001582153,0.02945714,0.0007544131,0.03287154],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002379491,"threshold_uncertainty_score":0.007960141,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02237429638773888,"score_gpt":0.2917273163706178,"score_spread":0.269353019982879,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}