{"id":"W2120109964","doi":"10.1186/1745-6215-13-199","title":"Rationale and design of the RIACT–study: a multi-center placebo controlled double blind study to test the efficacy of RItuximab in Acute Cellular tubulointerstitial rejection with B-cell infiltrates in renal Transplant patients: study protocol for a randomized controlled trial","year":2012,"lang":"en","type":"article","venue":"Trials","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"The Metabolomics Innovation Centre; University of Alberta","funders":"Universitätsklinikum Köln; Bundesministerium für Bildung und Forschung","keywords":"Medicine; Rituximab; Placebo; CD20; Internal medicine; T cell; B cell; Kidney; Renal function; Single Center; Clinical trial; Acute kidney injury; Immunology; Gastroenterology; Urology; Immune system; Antibody; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006360787,0.0002789101,0.002805362,0.000219908,0.00007188461,0.00002743682,0.0001003907,0.00004755596,0.00001501894],"category_scores_gemma":[0.0007499367,0.0001177324,0.0003066947,0.0002203748,0.00004859416,0.00009324399,0.00001118765,0.0001238272,6.796164e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004218356,"about_ca_system_score_gemma":0.0001180307,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001703345,"about_ca_topic_score_gemma":0.0002283183,"domain_scores_codex":[0.9946352,0.002456767,0.001987333,0.0002609666,0.0004435879,0.0002161278],"domain_scores_gemma":[0.9922315,0.006545139,0.0007797882,0.0002157043,0.000163439,0.00006440761],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8503011,0.09352669,0.04531711,0.00004552772,0.001462757,0.000004983607,0.008643313,0.0001191662,0.0005698701,0.000001522626,0.0000018217,0.000006059841],"study_design_scores_gemma":[0.9750093,0.01534883,0.003647112,0.0002566751,0.002961752,0.00000248318,0.0009010067,0.0001918933,0.001573578,0.000001474108,8.870799e-7,0.0001050674],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5354919,0.000003710535,0.0005248649,0.00002734719,0.00006562363,0.4638516,0.00002328568,0.000004281688,0.000007375705],"genre_scores_gemma":[0.6891437,9.974553e-7,0.0001397934,0.00001037163,0.00004319788,0.3105983,0.000009307036,0.00001318681,0.00004122144],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1536517,"threshold_uncertainty_score":0.4800988,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0845236552135892,"score_gpt":0.3812459284497503,"score_spread":0.2967222732361611,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}