{"id":"W2120223472","doi":"10.1158/1078-0432.ccr-08-2131","title":"Administration of Glucocorticoids to Ovarian Cancer Patients Is Associated with Expression of the Anti-apoptotic Genes <i>SGK1</i> and <i>MKP1/DUSP1</i> in Ovarian Tissues","year":2009,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":true,"ca_institutions":"Immunovaccine (Canada)","funders":"National Cancer Institute","keywords":"Dexamethasone; Glucocorticoid; Ovarian cancer; Biology; Glucocorticoid receptor; Apoptosis; Endocrinology; In situ hybridization; Internal medicine; Chemotherapy; Cancer; Pathology; Gene expression; Cancer research; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002074896,0.0001981676,0.0005303407,0.00009818213,0.0001487375,0.0002437529,0.00009371989,0.0001736079,0.001127949],"category_scores_gemma":[0.0005583758,0.00009193487,0.0001579222,0.000130744,0.0003944209,0.0001161005,0.0001213393,0.0005122032,0.0001369685],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002125361,"about_ca_system_score_gemma":0.000328765,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001330667,"about_ca_topic_score_gemma":0.0003451477,"domain_scores_codex":[0.9997874,0.00007545976,0.00001822627,0.00003468391,0.00004688157,0.0000373941],"domain_scores_gemma":[0.9995286,0.0001107572,0.0001792978,0.00003053615,0.00001618262,0.0001345826],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.1766157,0.00616012,0.1010364,0.0004999395,0.0003104515,0.0006277539,0.0002234898,0.0009027621,0.591386,0.00020497,0.0009299729,0.1211024],"study_design_scores_gemma":[0.01752636,0.3810957,0.4144008,0.00006908389,0.0004919681,0.004539659,0.000402519,0.002136453,0.1708101,0.0002606152,0.008221059,0.00004558196],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988092,0.0007245993,0.000130051,0.00003953888,0.00001268618,0.00003749901,0.00003971223,0.000006983135,0.0001996381],"genre_scores_gemma":[0.9991848,0.0002566714,0.0002517221,0.00004047062,0.00002551983,0.0000426046,0.00008610438,0.000001260473,0.0001109248],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001127949,"threshold_uncertainty_score":0.003773391,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0519615316995299,"score_gpt":0.4158934390545863,"score_spread":0.3639319073550564,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}