{"id":"W2120243182","doi":"10.1128/mcb.20.19.7353-7362.2000","title":"Control of hnRNP A1 Alternative Splicing: an Intron Element Represses Use of the Common 3′ Splice Site","year":2000,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Medical Research Council","keywords":"Minigene; Intron; RNA splicing; Exon; Biology; Splice site mutation; Alternative splicing; Exonic splicing enhancer; Splicing factor; Exon skipping; Polypyrimidine tract; Exon shuffling; Genetics; splice; Molecular biology; Gene; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002352733,0.0003628394,0.0002732398,0.0001647183,0.0001291881,0.000311564,0.0003272441,0.0002636296,0.001325957],"category_scores_gemma":[0.0002425196,0.0001453286,0.0002680698,0.00007984208,0.0003368394,0.0001277608,0.0003248082,0.0005414921,0.0004333796],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003114838,"about_ca_system_score_gemma":0.0002387932,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005885905,"about_ca_topic_score_gemma":0.000739208,"domain_scores_codex":[0.9997413,0.00006066651,0.00002395304,0.00007952521,0.00005495271,0.00003967214],"domain_scores_gemma":[0.9996547,0.0001157803,0.00008970335,0.0000460789,0.00003310521,0.00006057235],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004120582,0.00001204016,0.00007661626,0.000009855201,0.000001522371,0.00001498247,0.000004939681,0.0000241198,0.9992827,0.00005100507,0.000006593754,0.000474482],"study_design_scores_gemma":[0.00001045641,0.000101415,0.001813003,0.000003366992,0.000004885153,0.00009459985,0.00000973716,0.001032014,0.9960608,0.00002500723,0.0008419777,0.000002727703],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993629,0.0007314984,0.004246673,0.00006993406,0.00002556005,0.00002412504,0.0001981077,0.00009534407,0.0009795468],"genre_scores_gemma":[0.9932881,0.0003053919,0.003650976,0.0000415225,0.000008894351,0.00002773592,0.0003549542,0.00004000437,0.002282452],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001325957,"threshold_uncertainty_score":0.004435778,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01057693011863587,"score_gpt":0.2587938264737504,"score_spread":0.2482168963551146,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}