{"id":"W2120244315","doi":"10.1159/000149798","title":"Memantine Potentiates Agonist-Induced Ca<sup>2+</sup> Responses in HEK 293 Cells","year":2008,"lang":"en","type":"article","venue":"Cellular Physiology and Biochemistry","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research; Université de Sherbrooke; Heart and Stroke Foundation of Canada","keywords":"Memantine; Agonist; Intracellular; NMDA receptor; Chemistry; Extracellular; Pharmacology; HEK 293 cells; Calcium in biology; Receptor; Biophysics; Cell biology; Endocrinology; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002092407,0.0003675261,0.0007276454,0.0002315484,0.0001736342,0.0003448297,0.0004253624,0.0003454154,0.002961189],"category_scores_gemma":[0.000259829,0.0001894967,0.0004019293,0.0002424801,0.0002178969,0.0002641666,0.0002699883,0.0008116168,0.001202372],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002995312,"about_ca_system_score_gemma":0.0001574315,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005719602,"about_ca_topic_score_gemma":0.0007352533,"domain_scores_codex":[0.9996942,0.00005430403,0.00005759646,0.00004094754,0.00009053749,0.00006245541],"domain_scores_gemma":[0.9998329,0.00004585694,0.00003379422,0.00003348745,0.00003257331,0.00002134996],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002376396,0.00004450296,0.0000586774,0.0000681262,0.000006375031,0.0001103519,0.00002501046,0.00002808202,0.9984753,0.00003309394,0.00009753984,0.0008151318],"study_design_scores_gemma":[0.00004691212,0.0003651677,0.002284146,0.000008210692,0.00001888314,0.0003123497,0.00002822462,0.000441704,0.9937816,0.00003619139,0.002671399,0.000005345684],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9834615,0.004100588,0.002849777,0.0003502458,0.000230936,0.00006829292,0.001829743,0.0002931121,0.006815779],"genre_scores_gemma":[0.987792,0.002160797,0.003243292,0.0002441439,0.00007697495,0.0001025798,0.001438951,0.00007960098,0.004861567],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002961189,"threshold_uncertainty_score":0.009906173,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02549442772203075,"score_gpt":0.2363119405642174,"score_spread":0.2108175128421867,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}