{"id":"W2120245299","doi":"10.1074/jbc.m110.143388","title":"Insight into Invertebrate Defensin Mechanism of Action","year":2010,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":140,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Nautical Research Society","funders":"","keywords":"Defensin; Mechanism (biology); Invertebrate; Mechanism of action; Action (physics); Biology; Computational biology; Chemistry; Biochemistry; Ecology; Gene; Philosophy; In vitro; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001248779,0.000404367,0.0001687644,0.000169363,0.0001423217,0.0003693913,0.0002183663,0.0003655606,0.001006752],"category_scores_gemma":[0.00006321883,0.0001015182,0.0001973402,0.00008096856,0.0002786814,0.000296416,0.0001894934,0.000512348,0.0002733102],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003025716,"about_ca_system_score_gemma":0.0002106718,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000364007,"about_ca_topic_score_gemma":0.0002987993,"domain_scores_codex":[0.9999542,0.000006919853,0.000003714961,0.00001251895,0.00001121246,0.00001138733],"domain_scores_gemma":[0.999965,0.000006364336,0.000009980492,0.000003422686,0.000005926428,0.000009337756],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007678843,0.00002246226,0.001258573,0.0001460334,0.000007462203,0.0003204713,0.00003706694,0.0004894401,0.9911969,0.001310414,0.00005293152,0.005081506],"study_design_scores_gemma":[0.00005065991,0.001120777,0.04215796,0.0001199179,0.00007280487,0.003573604,0.0003751677,0.01050773,0.9086103,0.003350809,0.03002727,0.0000329756],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9564084,0.01517014,0.01941225,0.0005696437,0.00003836954,0.00004544951,0.0003490105,0.0000838693,0.00792277],"genre_scores_gemma":[0.9830005,0.005947621,0.008053502,0.0002491785,0.0000139905,0.00001931431,0.0002380444,0.000008175666,0.002469722],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001006752,"threshold_uncertainty_score":0.003367901,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02043157749470929,"score_gpt":0.2356361596097512,"score_spread":0.2152045821150419,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}