{"id":"W2120258242","doi":"10.1126/scitranslmed.3001022","title":"A Biosynthetic Alternative to Human Donor Tissue for Inducing Corneal Regeneration: 24-Month Follow-Up of a Phase 1 Clinical Study","year":2010,"lang":"en","type":"article","venue":"Science Translational Medicine","topic":"Corneal Surgery and Treatments","field":"Medicine","cited_by":405,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Regeneration (biology); Medicine; Biology; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003867419,0.0008979128,0.001743509,0.000685958,0.0005888099,0.0008395235,0.0005978713,0.001348211,0.001144557],"category_scores_gemma":[0.002276188,0.0002894356,0.001184854,0.0004672833,0.0008739184,0.0008882068,0.0002692049,0.001349362,0.0003549358],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003273876,"about_ca_system_score_gemma":0.000395307,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003270488,"about_ca_topic_score_gemma":0.0004185553,"domain_scores_codex":[0.9988716,0.0005344896,0.0001044056,0.0001153919,0.0001592017,0.0002148175],"domain_scores_gemma":[0.9984272,0.000533047,0.0003259678,0.00022127,0.0002001011,0.0002924594],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.1547588,0.2143958,0.04509263,0.001690117,0.001832611,0.004540815,0.001654124,0.003469277,0.2786339,0.0004468714,0.003192597,0.2902926],"study_design_scores_gemma":[0.02340855,0.8765215,0.04632778,0.00007824066,0.0007055487,0.002846383,0.0003432386,0.001480908,0.04463335,0.0002182965,0.003373191,0.00006303444],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932221,0.003818387,0.0009632372,0.000179921,0.00006557938,0.0006790998,0.00023798,0.00003733579,0.0007963341],"genre_scores_gemma":[0.9948776,0.001815352,0.0009410058,0.0003890903,0.00007850203,0.0004873945,0.0007909563,0.00001622333,0.0006037952],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003867419,"threshold_uncertainty_score":0.0204531,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1233338522551745,"score_gpt":0.456203729952707,"score_spread":0.3328698776975326,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}