{"id":"W2120275596","doi":"10.1016/j.molimm.2006.03.022","title":"RAG1/2 re-expression causes receptor revision in a model B cell line","year":2006,"lang":"en","type":"article","venue":"Molecular Immunology","topic":"Microbial metabolism and enzyme function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada Research Chairs; University of Toronto; York University","funders":"","keywords":"Recombination-activating gene; RAG2; Biology; Molecular biology; Gene rearrangement; Gene expression; Cell culture; Gene; Genetics; Recombination","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003965514,0.0005498813,0.0006610592,0.0004373501,0.0003070195,0.0007561403,0.000536561,0.0007081626,0.002481389],"category_scores_gemma":[0.0003777395,0.0002563899,0.0005339104,0.0004449861,0.0004129189,0.0003781855,0.0003367306,0.001828044,0.001184395],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004401829,"about_ca_system_score_gemma":0.0002082783,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001313114,"about_ca_topic_score_gemma":0.0007699215,"domain_scores_codex":[0.9992918,0.0001873586,0.00008296341,0.0001120798,0.0001585393,0.0001672622],"domain_scores_gemma":[0.9992312,0.0002995774,0.0001051807,0.000207651,0.00004906064,0.0001072625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002469538,0.00004721266,0.000103259,0.00001269499,0.000007291496,0.0001236275,0.00002085729,0.0001087687,0.9988909,0.00008735876,0.00004942119,0.0003016412],"study_design_scores_gemma":[0.0000291159,0.0002291347,0.0008108359,0.000001454456,0.00001483217,0.0003770726,0.00002994766,0.0008486817,0.996859,0.00003828239,0.0007561394,0.000005587748],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961818,0.0002795996,0.001610716,0.0001060683,0.00004343338,0.00002227119,0.000581087,0.0001788739,0.0009961148],"genre_scores_gemma":[0.9948912,0.0001847224,0.001733527,0.0000640635,0.00001498387,0.00003305808,0.001036923,0.00008709869,0.001954384],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002481389,"threshold_uncertainty_score":0.008301139,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005595672272545636,"score_gpt":0.2125039625894019,"score_spread":0.2069082903168562,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}