{"id":"W2120317081","doi":"10.1093/intimm/dxp092","title":"Histidine decarboxylase but not histamine receptor 1 or 2 deficiency protects from K/BxN serum-induced arthritis","year":2009,"lang":"en","type":"article","venue":"International Immunology","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Deutsche Forschungsgemeinschaft","keywords":"Histamine; Histidine decarboxylase; Arthritis; Histamine H4 receptor; Histamine receptor; Endocrinology; Histamine H2 receptor; Mast cell; Internal medicine; Receptor; Chemistry; Inflammatory arthritis; Immunology; Histidine; Medicine; Enzyme; Biochemistry; Antagonist","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002131506,0.0006937278,0.0004580434,0.0005270344,0.0001845469,0.0003400946,0.0002411243,0.000450457,0.001675189],"category_scores_gemma":[0.0001852837,0.000303679,0.0002088584,0.0001553496,0.0003054945,0.0002784225,0.000161044,0.0007622485,0.0004841],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000287656,"about_ca_system_score_gemma":0.000295413,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001056616,"about_ca_topic_score_gemma":0.001718631,"domain_scores_codex":[0.9998195,0.00002598581,0.00002208986,0.00003592189,0.00003272744,0.00006387052],"domain_scores_gemma":[0.9995776,0.00003471316,0.0001723058,0.00003898107,0.00002619542,0.0001501876],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008789398,0.0002161871,0.0004882269,0.00004166557,0.00001172475,0.00006904182,0.00001295855,0.00004971302,0.9968094,0.0000567622,0.00006687603,0.001298412],"study_design_scores_gemma":[0.0004660958,0.006832787,0.04544669,0.000057924,0.00009398397,0.000884332,0.0001112491,0.001394251,0.9420555,0.0001540659,0.002478735,0.0000243909],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974943,0.0008651115,0.0004705331,0.00006799673,0.0000335037,0.00001724557,0.0002740542,0.00008896119,0.0006882762],"genre_scores_gemma":[0.9942268,0.0007911972,0.0009171963,0.00009111441,0.00002092109,0.00002466814,0.0005712438,0.00003564683,0.003321219],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001675189,"threshold_uncertainty_score":0.005604088,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01537453015225519,"score_gpt":0.2358542014519383,"score_spread":0.2204796712996831,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}