{"id":"W2120376296","doi":"10.1093/molehr/gap101","title":"Viable iPSC mice: a step closer to therapeutic applications in humans?","year":2009,"lang":"en","type":"article","venue":"Molecular Human Reproduction","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Agence Nationale pour la Gestion des Déchets Radioactifs","keywords":"Biology; Induced pluripotent stem cell; Embryonic stem cell; Stem cell; Cell; Reprogramming; Epigenetics; Bioinformatics; Cell biology; Computational biology; Neuroscience; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000443193,0.0001742367,0.000150145,0.0001765974,0.0001406013,0.00004405188,0.0002737734,0.0001227563,0.00001939401],"category_scores_gemma":[0.00003222604,0.0001875003,0.0000798624,0.0003359682,0.00003707434,0.000005874099,0.00007325269,0.0001517512,0.00005500618],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005489802,"about_ca_system_score_gemma":0.0000339613,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003258522,"about_ca_topic_score_gemma":0.00003956256,"domain_scores_codex":[0.9980897,0.0001107653,0.0002735046,0.0009176419,0.000256846,0.0003515111],"domain_scores_gemma":[0.9986686,0.000002416793,0.00005898034,0.001068496,0.0001128822,0.00008870271],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003641758,0.0001825885,0.000505975,0.00001304453,0.00001746764,0.000005780117,0.00004250424,0.0005051177,0.9933777,0.0005282226,0.0004953698,0.004289753],"study_design_scores_gemma":[0.000487706,0.0004760007,0.0148424,0.0000165616,0.00001618054,0.00001292209,0.00007122645,0.00002315763,0.907604,0.001119556,0.07497397,0.0003562521],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98687,0.0008501286,0.00734817,0.0009964934,0.00005642508,0.001329167,0.000002438431,0.0000350315,0.002512175],"genre_scores_gemma":[0.9954515,0.00002481654,0.0006008134,0.0003952681,0.0002350195,0.0002075965,0.0001340062,0.00002894888,0.002922046],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08577369,"threshold_uncertainty_score":0.764604,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01407502860486011,"score_gpt":0.3012703878733515,"score_spread":0.2871953592684914,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}