{"id":"W2120376296","doi":"10.1093/molehr/gap101","title":"Viable iPSC mice: a step closer to therapeutic applications in humans?","year":2009,"lang":"en","type":"article","venue":"Molecular Human Reproduction","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Agence Nationale pour la Gestion des Déchets Radioactifs","keywords":"Biology; Induced pluripotent stem cell; Embryonic stem cell; Stem cell; Cell; Reprogramming; Epigenetics; Bioinformatics; Cell biology; Computational biology; Neuroscience; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006511626,0.0008068276,0.001552434,0.0007128847,0.0004331265,0.002844325,0.001049499,0.003496002,0.01063293],"category_scores_gemma":[0.003122884,0.0003935981,0.0005639529,0.0003583388,0.00279109,0.003350637,0.001278559,0.007816429,0.003854399],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005265566,"about_ca_system_score_gemma":0.001211393,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002857614,"about_ca_topic_score_gemma":0.0002700833,"domain_scores_codex":[0.9990112,0.0003105934,0.0001063591,0.0001119452,0.0003780792,0.00008185892],"domain_scores_gemma":[0.9981695,0.0007972286,0.0002055082,0.0003705609,0.0002082263,0.0002489375],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001160933,0.0007273607,0.002742612,0.002490737,0.0002353238,0.003417523,0.0006881379,0.0008261972,0.1437373,0.2970792,0.125351,0.4215437],"study_design_scores_gemma":[0.0004197019,0.001532987,0.001352382,0.001255407,0.0001944048,0.008399818,0.0004626686,0.0008375074,0.04562741,0.08983812,0.8499986,0.0000810182],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.05398378,0.3243897,0.2193275,0.313203,0.01707027,0.0007981384,0.002728359,0.004480076,0.06401911],"genre_scores_gemma":[0.273374,0.3190322,0.2272283,0.1316382,0.01015389,0.001507421,0.00411265,0.00201928,0.03093406],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01063293,"threshold_uncertainty_score":0.03557068,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01407502860486011,"score_gpt":0.3012703878733515,"score_spread":0.2871953592684914,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}